Causality applies everywhere, and it is hard even to imagine a world in which it does not. Yet, one must acknowledge that life also is creative and diverse. Un-der these circumstances, the question emerges whether causal models can ex-plain life's creativity and diversity. Some life scientists say yes, yet many hu-manities scholars cast doubts or have posited that they have reached the end of theory. Here, I build on common empirical observations as well as long-accumulated modeling experience, and I review and further develop a unified framework for causal modeling that applies to all sciences including physics, biology, the sciences of the city, and the humanities.