Culture of cultures: Antimicrobial prescription practices in hospitalised patients at level 1 trauma centre

Bajpai, Vijeta; Gupta, Deepak; Bindra, Ashish; Malhotra, Rajesh; Mathur, Purva

doi:10.4103/jpsic.jpsic_6_18

Cited by 2 publications

(2 citation statements)

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“…The present study discusses the important issue of how often antimicrobial prescriptions are based on culture results. Similar to our study, Bajpai et al noted that 43.9% of the patient’s culture samples were not sent before starting antibiotic treatment [ 11 ]. Another study done by Garg et al came out with a similar finding: 41.6% of the patients were treated with antibiotics empirically without sending any microbiology culture investigations [ 12 ].…”

Section: Discussionsupporting

confidence: 88%

Culture of Cultures: A Small Step Towards Augmenting Diagnostic Stewardship

Cheemalapati,

S R

et al. 2024

Cureus

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Laboratories with a well-established diagnostic stewardship program for culture and the antimicrobial susceptibility test (C-AST) play a key role in guiding clinicians to institute specific targeted therapy. Blood culture is one of the most critical investigations performed at a microbiology laboratory. Therefore, it is particularly important to develop a robust diagnostic stewardship model for the blood culture laboratory division. Aiming at this hypothesis, this hospital-based clinical audit carried out within the Department of General Medicine, centered on the critical domain of antimicrobial stewardship (AMSP). The audit's primary objective was to systematically evaluate prevailing practices and pinpoint areas necessitating refinement in the administration of antimicrobial agents. Employing a meticulous approach involving exhaustive data scrutiny and feedback mechanisms, the audit unearthed strategic opportunities to optimize prescription patterns, curtail unwarranted antimicrobial utilization, and fortify adherence to established guidelines. The subsequent execution of targeted interventions, encompassing educational initiatives and routine performance feedback, culminated in a noteworthy enhancement of antimicrobial prescribing practices. These outcomes unequivocally underscore the efficacy of the audit in cultivating a milieu of judicious antimicrobial utilization, thereby augmenting patient care and mitigating antibiotic resistance within the department.

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Section: Discussionsupporting

confidence: 88%

Culture of Cultures: A Small Step Towards Augmenting Diagnostic Stewardship

Cheemalapati,

S R

et al. 2024

Cureus

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“…Similar observations have been reported from India and outside. In a retrospective study over 10 months in a level 1 trauma centre in India, only 13.5% of antimicrobial prescriptions were based on culture reports [26]. In another antibiotic utilization study in Saudi Arabia, antimicrobial modification based on available culture results was performed in only 12% of patients [27].…”

Section: Table 3: Bacterial Culture Rate (%) In Various Countriesmentioning

confidence: 99%

Impact of an Anti-Microbial Stewardship Program on Targeted Antimicrobial Therapy in a Tertiary Care Health Care Institute in Central India

Garg¹,

Singh²,

Kumar³

et al. 2021

Cureus

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IntroductionAntimicrobial resistance (AMR) has become a global pandemic. In order to identify this menace, World Health Organisation (WHO) has developed the Global Action Plan on AMR (GAP AMR). Antimicrobial stewardship programs (AMSP) have been identified as a decisive tool for combating AMR. One of the most efficient measures of these programs has been the implementation of point prevalence surveys (PPS) of antibiotic usage and subsequent audit feedback. The present study was undertaken to identify the impact of AMSP on curtailing of empirical usage of antibiotics and the augmentation of targeted therapy. MethodsIt is an observational, cross-sectional study comprising 1396 patients. The microbiology culture details and anti-microbial-sensitivity results were recorded. Antibiotic prescriptions were recorded in each patient during their hospital stay. ResultOut of 1396 patients treated over four quarters (Q1-Q4), 711 (50.9%) patients were on antibiotics, and among them, only 415 patients were subjected to any microbiological cultures with an overall bacterial culture rate (BCR) of 58.3%, and 296 patients (41.6%) were treated with antibiotics empirically without sending any samples for bacterial culture. There was a statistically significant rise in BCR from 47.3% in the first quarter to 77.6% in the fourth quarter. Sending specimens for blood culture increased significantly from 29.2% in Q1 to 37.6% in Q4. After receiving culture reports, 72.3% of cases continued with the same antibiotic, the antibiotic was changed in 19.9% of cases, and the antibiotic was stopped in 7.8% of cases. ConclusionThere was a strong positive impact of AMSP in curtailment of empirical usage of antibiotics and augmenting targeted therapy as evidenced by the significant rise in BCR over Q1-Q4 PPS as well as a significant rise in ordering for blood culture over the same time period.

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Culture of cultures: Antimicrobial prescription practices in hospitalised patients at level 1 trauma centre

Cited by 2 publications

References 1 publication

Culture of Cultures: A Small Step Towards Augmenting Diagnostic Stewardship

Culture of Cultures: A Small Step Towards Augmenting Diagnostic Stewardship

Impact of an Anti-Microbial Stewardship Program on Targeted Antimicrobial Therapy in a Tertiary Care Health Care Institute in Central India

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