Culturomics revealed the bacterial constituents of the microbiota of a 10-year-old laboratory culture of planarian species S. mediterranea

Kangale, Luis Johnson; Raoult, Didier; Fournier, Pierre‐Edouard; Ghigo, Éric

doi:10.1038/s41598-021-03719-5

Cited by 3 publications

(1 citation statement)

References 110 publications

(84 reference statements)

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“…Pedobacter, it appears, is a broadly conserved constituents of the microbiome in disparate Planaria flatworms as Pedobacter was also detected in the European planarian Schmidtea mediterranea (Kangale, 2020, Kangale 2021. Collectively these results indicate antibiotic treatment affects the planarian microbiome and that this disruption may alter behavior and behavioral responses to addictive substances.…”

Section: Resultsmentioning

confidence: 79%

Influence of Microbiome on Withdrawal-Like Behavior in Planaria

Sosa,

Pisciotta,

Guerra-Solano

et al. 2023

Preprint

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The microbiome of animals can influence health status, disease susceptibility and can also influence host behavior. This study investigates the effect of microbiome alteration on animal behavior using the planarian model system. For this,Girardia tigrina(Brown Planaria) andPhagocata gracilis(Black Planaria) were investigated. These flatworms possess a primitive nervous system and exhibit similar addictive and withdrawal behaviors to mammals. Here we tested the hypothesis that alteration of planarian microbiome using the broad-spectrum antibiotics kanamycin and ampicillin could influence the worms’ behavior and withdrawal response to nicotine. After antibiotic treatment period of seven days, the behavior and withdrawal response of four groups of brown and black planaria was analyzed by recording the worms’ motility on a 1 cm2grid. Results support the hypothesis as treatment significantly altered behavior in black worms. The microbiomes of antibiotic treated planaria were analyzed using conventional culture techniques, microscopy and metagenomic methods. Alpha proteobacteria including Sphingomonadaceae were detected in both Brown and Black planarians. This study suggests chemotherapeutic alteration of an animal’s microbiome can influence motility behavior and withdrawal responses to addictive substance and sheds light on the species composition of Planarian microbiomes.

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Section: Resultsmentioning

confidence: 79%

Influence of Microbiome on Withdrawal-Like Behavior in Planaria

Sosa,

Pisciotta,

Guerra-Solano

et al. 2023

Preprint

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Effects of regulating gut microbiota by electroacupuncture in the chronic unpredictable mild stress rat model

Duan,

Wang,

et al. 2024

Neuroscience

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Multiomics data integration, limitations, and prospects to reveal the metabolic activity of the coral holobiont

Williams

2024

FEMS Microbiology Ecology

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Since their radiation in the Middle Triassic period ∼ 240 million years ago, stony corals have survived past climate fluctuations and five mass extinctions. Their long-term survival underscores the inherent resilience of corals, particularly when considering the nutrient-poor marine environments in which they have thrived. However, coral bleaching has emerged as a global threat to coral survival, requiring rapid advancements in coral research to understand holobiont stress responses and allow for interventions before extensive bleaching occurs. This review encompasses the potential, as well as the limits, of multiomics data applications when applied to the coral holobiont. Synopses for how different omics tools have been applied to date and their current restrictions are discussed, in addition to ways these restrictions may be overcome, such as recruiting new technology to studies, utilizing novel bioinformatics approaches, and generally integrating omics data. Lastly, this review presents considerations for the design of holobiont multiomics studies to support lab-to-field advancements of coral stress marker monitoring systems. Although much of the bleaching mechanism has eluded investigation to date, multiomic studies have already produced key findings regarding the holobiont's stress response, and have the potential to advance the field further.

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Culturomics revealed the bacterial constituents of the microbiota of a 10-year-old laboratory culture of planarian species S. mediterranea

Cited by 3 publications

References 110 publications

Influence of Microbiome on Withdrawal-Like Behavior in Planaria

Influence of Microbiome on Withdrawal-Like Behavior in Planaria

Effects of regulating gut microbiota by electroacupuncture in the chronic unpredictable mild stress rat model

Multiomics data integration, limitations, and prospects to reveal the metabolic activity of the coral holobiont

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