This research focuses on addressing the limitations of conventional physical sensors and developing a virtual water flow rate prediction technology. With HVAC systems being increasingly adopted, research on optimizing control settings based on load variations is critical. Existing systems often operate based on peak load conditions, leading to energy overconsumption in partial load scenarios. Physical sensors used for water flow measurement face challenges such as installation difficulties in constrained spaces and increased costs in large buildings. Virtual water flow rate prediction technology offers a cost-effective solution by leveraging in situ measurement data instead of extensive physical sensors. To achieve this, a test bed with a pump, valve, and heat pump was used, controlled via a BAS. Water flow rate was measured using an ultrasonic flow meter, and differential pressure was recorded using pressure gauges. Equations were developed to replace differential pressure values with valve opening rates and pump speeds by deriving performance curves and differential pressure ratio equations. Measurement uncertainty was calculated to assess the reliability of the experimental setup. Various test numbers were created to evaluate the virtual water flow rate model under controlled conditions. The results showed that relative errors ranged from 0.32% to 10.54%, with RMSE, MBE, and CvRMSE meeting all threshold criteria. The virtual water flow rate model demonstrated strong predictive accuracy and reliability, supported by an R2 value close to 1. This research confirms the effectiveness of the proposed model for reducing the dependence on physical sensors while enabling accurate water flow rate predictions in HVAC systems.