Cumulative live birth rates in cohorts of patients treated with in vitro fertilization or intracytoplasmic sperm injection

Witsenburg, C.P.J.; Dieben, Sandra; Westerlaken, Lucette van der; Verburg, Harjo; Naaktgeboren, N.

doi:10.1016/j.fertnstert.2005.02.013

Cited by 79 publications

(70 citation statements)

References 18 publications

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“…15 In a Dutch study, 90% of the pregnancies achieved with the use of assisted reproductive technology were conceived within the first three cycles. 16 A recent randomized, controlled trial in which embryos were randomly assigned to be transferred fresh versus thawed showed no significant difference in the implantation or pregnancy rate. 17 This finding is similar to our results for autologous oocytes; however, for cycles that used donor oocytes, the live-birth rate was higher for fresh embryos than for thawed embryos.…”

Section: Discussionmentioning

confidence: 99%

“…First, because of the nature of the database, these outcomes do not account for naturally conceived pregnancies, which have been reported to occur in 9 to 28% of women who discontinue treatment with assisted reproductive technology. 15,16,20 Second, body-mass index was not considered in these analyses, since it was not included in the SART CORS database until 2007, but it is known to affect success rates. 21,22 Third, we evaluated oocyte state and oocyte source separately.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cumulative Birth Rates With Linked Assisted Reproductive Technology Cycles

Luke

Brown

Wantman

et al. 2012

Obstetrical &Amp; Gynecological Survey

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cumulative Birth Rates With Linked Assisted Reproductive Technology Cycles

Luke

Brown

Wantman

et al. 2012

Obstetrical &Amp; Gynecological Survey

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“…over the number of couples who received this specific cycle within a certain time frame [28]. The cumulative LBR (conservative estimate) is calculated by dividing the number of live neonates up to and including a specific IVF cycle over the number of couples who had received these IVF cycles [28][29][30]. Another LBR calculation method assumes that couples who did not return for subsequent IVF cycles had the same chance of a live birth as those who did return for treatment.…”

Section: Ivf and Lbrsmentioning

confidence: 99%

Success of In Vitro Fertilization: A Researched Science or a Performance Indicator

Salam¹

2017

J Clin Gynecol Obstet

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Divisions of reproductive medicine often perceive the live birth rate (LBR) as the single most important performance indicator for any infertility clinic, and it reflects on the quality of their services. Due to this perception, some infertility experts might refrain from disclosing these rates in publications as a researched science. Infertility experts might not be familiar with the various methods of reporting LBR as an outcome of in vitro fertilization (IVF) and therefore should be aware of these methods. Moreover, infertility experts might miss to take into account some couple and disease-related characteristics that could be successful determinants of this LBR. This is a brief review on infertility and its impact on married couples, as well as the history and description of IVF. We also present infertility experts with various methods of reporting LBR and shed light on some of the couple and disease-related factors associated with higher LBRs after IVF as reported in literature.

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“…Nach Daten des DIR 2005 (Deutsches IVF-Register, DIR Jahrbuch 2006) liegt die Schwangerschaftsrate (pro Embryotransfer) nach Transfer von 2 oder 3 Embryonen zwischen 28 und 30%. Die Wahrscheinlichkeit einer Lebendgeburt pro einzelner IVF-Behandlung ist ebenfalls gering, in der Regel sind mehrere aufeinanderfolgende Behandlungen (und Embryonenübertragungen) notwendig, um die Wahrscheinlichkeit der Lebendgeburt weiter zu erhöhen [1]. Mit jedem weiteren Behandlungszyklus nimmt zwar die Wahrscheinlichkeit einer Lebendgeburt zu, aber auch physische, psychische und finanzielle Belastungen sowie medizinische Risiken, sodass ein signifikanter Teil der Paare die Behandlung vorzeitig abbricht.…”

Section: Geringe Effizienz Der Ivf-behandlungunclassified

Reproduktionsmedizin: Fortschritt wagen – Grenzen erkennen

Diedrich

Griesinger

2008

Gynäkologe

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Reproduktionsmedizin: Fortschritt wagenGrenzen erkennen Leitthema Seit der Einführung von In-vitro-Fertilisation und Embryotransfer im Jahre 1978 hat die Reproduktionsmedizin große Fortschritte in den Mög-lichkeiten der Behandlung ungewollter Kinderlosigkeit gemacht. Entwickelt wurden neue diagnostische Verfahren, wie die Präimplantationsdia-gnostik, und Behandlungsmöglich-keiten, wie die intrazytoplasmatische Spermieninjektion (ICSI) oder die Kryokonservierung von Eizellen und Embryonen. Von diesen Fortschritten haben viele hoffnungslos ungewollt kinderlose Paare profitiert, und es gibt heute weltweit über 3 Mio. Kinder, die durch die Hilfen der Reproduktionsmedizin geboren wurden. Deutschen Paaren mit Kinderwunsch ist die Partizipation an diesem Fortschritt durch die Regelungen des Embryonenschutzgesetzes (ESchG) teilweise verwehrt, und es ist deshalb dringend erforderlich, dieses Strafgesetz dem aktuellen Stand der Wissenschaft und Technik anzupassen. Risikoerhöhung Bluthochdruck in der Schwangerschaft~2,5-fach Präeklampsie~2,5-fach Nachblutung nach Geburt~2-fach Notwendigkeit eines Kaiserschnitts~3-fach Intensivmedizinische Betreuung~15-fach Postnatale Depression~3-fach Tab. 2 Fetale Risikoerhöhung durch Zwillingsschwangerschaften im Vergleich zu Einlingsschwangerschaften. (Mod. nach [3, 4, 5, 6, 7, 8, 9]) Risikoerhöhung Frühgeburtlichkeit (<37. Woche)~10-fach Niedriges Geburtsgewicht (<2500 g)~7-10-fach Frühkindliche Hirnschädigung (Zerebralparese)~3-10-fach Atemnotsyndrom des Neugeborenen~5-7-fach Blutvergiftung (Sepsis)~3-fach Bleibende, schwere Behinderung (alle) 1,5-2-fach lingsschwangerschaften in nicht unerheblichem Umfang.

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Cumulative live birth rates in cohorts of patients treated with in vitro fertilization or intracytoplasmic sperm injection

Cited by 79 publications

References 18 publications

Cumulative Birth Rates With Linked Assisted Reproductive Technology Cycles

Cumulative Birth Rates With Linked Assisted Reproductive Technology Cycles

Success of In Vitro Fertilization: A Researched Science or a Performance Indicator

Reproduktionsmedizin: Fortschritt wagen – Grenzen erkennen

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