Cumulative Skin Irritation Test of Sanitary Pads in Sensitive Skin and Normal Skin Population

Abstract

The test materials produced similar degrees of skin irritation among both groups. Overall, there was no statistically significant difference in skin compatibility when the two feminine hygiene product test patches were worn by self-declared normal and sensitive skin groups.

Sensitive skin: new findings yield new insights

“…Testing has been done primarily on normal subjects, bringing into question the need to focus on examining populations that may be sometimes inherently more sensitive to irritant effects (22). Some studies did compare the irritation potential of products between self-declared sensitive-skin to nonsensitive-skin subjects (104,105). A summary of current methodologies used to identify sensitive skin is shown in Table 8.4.…”

Sensitive skin

“…The authors proposed the thermal sensation test, the stinging test [8], an occlusive application of sodium lauryl sulfate, an evaluation of the itch response, the washing and exaggerated immersion test, TEWL assessment, corneometry, laser Doppler velocimetry, colorimetry, squamometry, corneosurfametry and quantitative sensory testing (QST) to diagnose or quantify sensitive skin [4,8,37]. However, the latter method is especially very time consuming and most likely limited to clinical trials.…”

Putative neuronal mechanisms of sensitive skin

“…To date, no constitutional factors have been identified in sensitive skin (12)(13)(14)(15)(16)(17). Epidemiological studies investigating the correlations between sensitive skin and sex, age or race have shown contradictory results (1,(12)(13)(14)(15)(16)(17). Some studies have suggested that women tend to have enhanced nociception and more frequently have sensitive skin (1,16), while other studies indicated that males have a significantly higher incidence of sensitive skin (17).…”

“…An overview of the possible diagnostic tests for sensitive skin was previously presented in two review articles (12,13). The recommended diagnostic tests for sensitive skin include: the thermal sensation test, the stinging test (9), occlusive application of sodium lauryl sulphate, evaluation of the itch response, the washing and exaggerated immersion test, transepidermal water loss (TEWL), corneometry, laser Doppler velocimetry, colorimetry, squamometry, corneosurfametry and quantitative sensory testing (QST) (12–14). Of these tests, QST is very time‐consuming, which may limit its application to clinical trials.…”

“…To date, no constitutional factors have been identified in sensitive skin (12–17). Epidemiological studies investigating the correlations between sensitive skin and sex, age or race have shown contradictory results (1,12–17).…”