Cuprous Oxide Nanoparticles Decorated Fabric Materials with Anti-biofilm Properties

Abstract

Considering the global spread of bacterial infections, the development of anti-biofilm surfaces with high antimicrobial activities is highly desired. This work unraveled a simple, sonochemical method for coating Cu2O nanoparticles (NPs) on three different flexible substrates: polyester (PE), nylon 2 (N2), and polyethylene (PEL). The introduction of Cu2O NPs on these substrates enhanced their surface hydrophobicity, induced ROS generation, and completely inhibited the growth of sensitive (Escherichia coli and Staphyloccocus aureus) and drug-resistant (MDR E. coli and MRSA) planktonic and biofilm. The experimental results confirmed that Cu2O-PE exhibited complete biofilm mass reduction ability for all four strains, whereas Cu2O-N2 showed more than 99% biomass inhibition against both drug-resistant and sensitive pathogens in 6 h. Moreover, Cu2O-PEL also indicated a 99.95, 97.73, 98.00, and 99.20% biomass reduction of MRSA, MDR E. coli, E. coli, and S. aureus, respectively. All substrates were investigated for time-dependent inhibitions, and the associated biofilm mass and log reduction were evaluated. The mechanisms of Cu2O NP action against the mature biofilms include the generation of reactive oxygen species (ROS) as well as electrostatic interaction between Cu2O NPs and bacterial membranes. The current study could pave the way for the commercialization of sonochemically coated Cu2O NP flexible substrates for the prevention of microbial contamination in hospitals and industrial environments.

Copper-Nanoparticle-Coated Melt-Blown Facemask Filter with Antibacterial and SARS-CoV-2 Antiviral Ability

“…The suspensions were serially diluted, and then 10 μL of each was suspended on Mueller−Hinton agar plates and incubated at 37 °C and 5% CO 2 for 24 h. After incubation, the colony-forming units (CFU/mL) were calculated. 29 Reusability. In order to evaluate the effect of standard sterilization methods including UV irradiation and autoclaving on the biocompatibility and antibacterial activity of coated melt-blown surfaces, coated samples were prepared in two groups.…”

“…The inoculum was removed, and samples were rinsed gently with sterile PBS for 1 min to remove unattached cells, then placed in sterile tubes containing 1 mL of PBS, and vortexed for 1 min. The suspensions were serially diluted, and then 10 μL of each was suspended on Mueller–Hinton agar plates and incubated at 37 °C and 5% CO 2 for 24 h. After incubation, the colony-forming units (CFU/mL) were calculated …”

Waste-Derived Sustainable Fluorescent Nanocarbon-Coated Breathable Functional Fabric for Antioxidant and Antimicrobial Applications

“…With the advancement of textile industrialization and technology, the popularity for functional textiles has increased significantly, along with the global demand for multifunctional textiles used for a variety of purposes such as health care, sports, UV protection, personal care products, outdoor activities, and military. , Several research methods have focused on the modification of textiles to have multifunctional properties such as flame retardant, self-cleaning, antibacterial, , and water repellent properties. To treat textiles, researchers have utilized a variety of chemicals, such organometallics, phenols, inorganic salts, heterocyclics with anionic functionalities, urea, formaldehyde derivatives, and amines …”

Zirconium-Coated β-Cyclodextrin Nanomaterials for Biofilm Eradication

“…Over the past few years, billions of microbial infections have arisen every year, with over 70% of infections caused by bacterial biofilms. − Compared with planktonic or free-floating bacteria, such pathogens live in distinct metabolic states and physical environments, , and their eradication is very difficult, a considerable burden on healthcare systems. , The extended use of antibiotics can initiate biofilm formation and increase the bacterial persistence issue associated with these infections. − Therefore, the development of a novel antimicrobial strategy to tackle bacterial biofilm infections is urgently needed for medical implant development. Conventional antibiotics are no longer considered “a silver bullet”, and there is an urgent need for a new class of antimicrobial agents to target antibiotic-resistant microorganisms.…”