Curative role of lactulose, L-carnitine, alpha-lipoic acid and combination of L-carnitine and alpha-lipoic acid in a rat model of acute hepatic encephalopathy: Biochemical observations

Abstract

Purpose: To determine whether a combination L-carnitine and α-lipoic acid (ALA) can alleviate the toxic effects of thioacetamide (TAA) via their potent antioxidant

<p>The Potential Neuroprotective Role of Citicoline in Hepatic Encephalopathy</p>

“…L-carnitine, taurine, carnosine, N-acetyl cysteine, and α-lipoic acid supplementation have been tested as hepatic/neuroprotective agents in animal models or clinical studies. [6][7][8][9][10][11][12][13][14] Citicoline is a principal intermediate in the biosynthesis pathway of phosphatidylcholine. 15 Several investigations revealed that citicoline acts as a neurovascular protecting agent.…”