Curative Value of Ampicillin in Small Animals and Susceptibility of Isolated Organisms to Ampicillin

Abstract

SUMMARY rized as follows.1. Of the 68 animals tested, 54 recovered well by the treatment of ampicillin. Good results were obtained from most of the animals affected with alimentary and urinary tract infections and from 80% or more of the animals suffering from suppurative dermatitides and respiratory tract infections. Only poor responses were observed in most of the cases of abscess, otitis and endometritis.2. Various species of Staphylococcus, Proteus, Escherichia, Streptococcus, and Pseudoxnonas were isolated from 32 of 39 animals examined prior to the treatment. Staphylococci and Gram-negative bacilli were frequently isolated from suppurative dermatitides and respiratory tract infections, respectively.3. Ampicillin was significantly effective against about 90% of the strains, inhibiting the growth of both Gram-negative and positive organisms. Its antimicrobial activity was similar to that of tetracycline or chloramphenicol.