2014
DOI: 10.1155/2014/761608
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Curcumin: A Potential Candidate in Prevention of Cancer via Modulation of Molecular Pathways

Abstract: Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact cause of cancer development and progression is not fully known. But it is thought that cancer occurs due to the structural and functional changes in the genes. The current approach to cancer treatment based on allopathic is expensive, exhibits side effects; and may also alter the normal functioning of genes. Thus, a safe and effective mode of treatment is needed to control the cancer development and progression. Some m… Show more

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Cited by 159 publications
(99 citation statements)
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References 165 publications
(152 reference statements)
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“…Curcumin (diferuloylmethane, Cur) is a non-flavonoid polyphenol derived from turmeric plants that demonstrates great potential in tumorigenesis and tumor progression (6,7). Accumulating evidence has indicated that Cur can sensitize numerous radioresistant tumor cells, including NPC (8)(9)(10).…”
Section: Introductionmentioning
confidence: 99%
“…Curcumin (diferuloylmethane, Cur) is a non-flavonoid polyphenol derived from turmeric plants that demonstrates great potential in tumorigenesis and tumor progression (6,7). Accumulating evidence has indicated that Cur can sensitize numerous radioresistant tumor cells, including NPC (8)(9)(10).…”
Section: Introductionmentioning
confidence: 99%
“…[65][66][67] Saffron and its active constituents perform an important role in the inhibition of tumour development and progression Table 2. In this regard, numerous findings based on animal models confirmed that saffron plays a role in prevention of various types of tumour.…”
Section: Anti-tumour Activitymentioning
confidence: 99%
“…Linn) which is used in the preparation of curry, an East Indian dish. Curcumin possesses anti-inflammatory and antioxidant activities, and has been studied as a chemoprevention agent in several cancer models (Li, Wicha, Schwartz, & Sun, 2011;Rahmani, Al Zohairy, Aly, & Khan, 2014;Attari, Zahmatkesh, Aligholi et al, 2015;Gupta, Kismali, & Agarwal, 2013) (Figure 1). Vol.…”
Section: Curcuminmentioning
confidence: 99%