2007
DOI: 10.1096/fasebj.21.5.a407
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Curcumin inhibits pro‐fibrotic phenotypes in human lung fibroblasts

Abstract: Fibrosis of the lung is a common endpoint for a variety of diseases. Current available treatments have been mostly ineffective. Proliferation of pulmonary fibroblasts, enhanced production of extracellular matrix components by these cells, and differentiation of fibroblasts to myofibroblasts results in tissue fibrosis. Curcumin, a component of the widely used Ayurvedic compound turmeric, is a potent biological molecule. Numerous studies have characterized its effects on a wide variety of cellular processes and … Show more

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