Curcumin-loaded core-shell biopolymer nanoparticles produced by the pH-driven method: Physicochemical and release properties

Li, Zhenpeng; Lin, Quanquan; McClements, David Julian; Fu, Yuying; Li, Teng; Chen, Guowen

doi:10.1016/j.foodchem.2021.129686

Cited by 85 publications

(33 citation statements)

References 37 publications

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“…The result is in accordance with the study carried out by Yuan et al (2021) , who demonstrated the bioaccessibility of curcumin in zein NPs coated with tea saponins was 60.83%, which was significantly higher than that of free curcumin (below 15%). However, the release rates of curcumin loaded in zein/sodium alginate and zein/sodium caseinate NPs fabricated by pH-driven method were above 90% ( Li et al (2021) . In terms of the reason for these different results, in addition to the different characteristics of coating materials, the differences in vitro digestion models and preparation methods should be taken into consideration.…”

Section: Resultsmentioning

confidence: 99%

Tremella polysaccharides-coated zein nanoparticles for enhancing stability and bioaccessibility of curcumin

Wei

Sun

et al. 2022

Current Research in Food Science

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Section: Resultsmentioning

confidence: 99%

Tremella polysaccharides-coated zein nanoparticles for enhancing stability and bioaccessibility of curcumin

Wei

Sun

et al. 2022

Current Research in Food Science

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“…At the end of intestinal digestion, the values of release rate of EGCG from Zein-EGCG and E-Z/G 1:1 complex nanoparticles reached 87.38 and 84.23%, respectively. This may be because the interaction between GA and zein was weakened with the change of environmental pH, allowing trypsin to damage the structure of zein and resulting in the massive release of EGCG [ 48 , 49 , 50 ].…”

Section: Resultsmentioning

confidence: 99%

Encapsulation of EGCG by Zein-Gum Arabic Complex Nanoparticles and In Vitro Simulated Digestion of Complex Nanoparticles

Jin

Liu

Tong

et al. 2022

Foods

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Epigallocatechin gallate (EGCG) has many excellent qualities such as its antitumor, antiradiation and anti-oxidation properties, but its application is limited because its oral bioavailability is low and stability is poor. In this paper, zein and gum arabic (GA) were used as wall materials to prepare Zein-GA complex nanoparticles for encapsulating and protecting the EGCG. The particle size of Zein-GA-EGCG complex nanoparticles ranged from 128.03–221.23 nm, and the EGCG encapsulation efficiency reached a maximum of 75.23% when the mass ratio of zein to GA was 1:1. The FTIR and XRD results illustrated that the components of the Zein-GA-EGCG complex nanoparticles interacted by electrostatic, hydrogen bonding, and hydrophobic interactions. The EGCG release rate of Zein-GA-EGCG nanoparticles (16.42%) was lower than that of Zein-EGCG (25.52%) during gastric digestion, and a large amount of EGCG was released during intestinal digestion, suggesting that the Zein-GA-EGCG nanoparticles could achieve the sustained release of EGCG during in vitro digestion. Hence, using Zein-GA complexes to encapsulate EGCG effectively increased the encapsulation efficiency of EGCG and realized the purpose of sustained release during simulated gastrointestinal digestion.

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“…The XRD patterns were measured by X‐ray diffractometer (D/max 200PC, Rigaku, Tokyo, Japan) according to the method of Li et al . (2021) with slight modifications. The samples were scanned from 3° to 55° (2θ) at the scan rate of 4°/min.…”

Section: Methodsmentioning

confidence: 99%

Preparation and characterisation of curcumin‐loaded pea protein‐zein nanocomplexes using pH‐driven method

Zhao

Han

Yin

et al. 2022

Int J of Food Sci Tech

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Summary The nanocomplexes of hydrophilic pea protein (Pp) and hydrophobic zein were prepared to encapsulate curcumin (Cur) by the pH‐driven method. The properties of pea protein‐zein complex were affected by many factors, of which mass ratio was one of the most important factors. The nanocomplexes with a mass ratio Pp to zein of 8:2 showed a smaller size (near 100 nm) and a higher stability than individual Pp nanoparticles. The solubility of Cur was significantly improved by the nanocomplexes prepared by this method. In neutral aqueous solution, the solubility of Cur encapsulated with the nanocomplex reached 652 μg mL−1, and the nanocomplexes had excellent re‐dispersibility. The main forces for the formation of nanocomplexes were hydrophobic interactions and hydrogen bonds, and the Cur existed in amorphous state in the nanocomplexes. The Cur coated with protein complexes had higher storage stability and thermal stability than Cur loaded with single protein, indicating the stronger protection on Cur provided by protein complexes. Furthermore, the nanocomplexes exhibited an improved antioxidant activity after in vitro simulated digestion. Thus, the nanocomplexes prepared by a simple and safe pH‐driven method could be used for functional protection and delivery of hydrophobic bioactive compounds.

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Curcumin-loaded core-shell biopolymer nanoparticles produced by the pH-driven method: Physicochemical and release properties

Cited by 85 publications

References 37 publications

Tremella polysaccharides-coated zein nanoparticles for enhancing stability and bioaccessibility of curcumin

Tremella polysaccharides-coated zein nanoparticles for enhancing stability and bioaccessibility of curcumin

Encapsulation of EGCG by Zein-Gum Arabic Complex Nanoparticles and In Vitro Simulated Digestion of Complex Nanoparticles

Preparation and characterisation of curcumin‐loaded pea protein‐zein nanocomplexes using pH‐driven method

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