Curcuminoids-conjugated multicore magnetic nanoparticles: Design and characterization of a potential theranostic nanoplatform

Superparamagnetic iron oxide nanoparticles for magnetic hyperthermia: recent advancements, molecular effects, and future directions in the omics era

“…This nanoplatform showed promising results in terms of magnetic hyperthermia and fluorescent imaging, but further in vitro and in vivo studies are necessary. 45 Another interesting example of a stabilisation and delivery strategy for SPIONs is represented by “earthicles”, which are nanocomposites consisting of zero-valent iron, silica, and carbon, with a composition that resembles the stratified structure of the Earth (and thus the reason for their name). Wu et al prepared earthicles with a ferrofluid core containing SPIONs instead of a zero-valent iron core; the coating, composed of a double shell of silicate mesolayers (SiO 2 ) and carbon (C) crust, was kept similar to the original earthicles’ composition.…”

Magnetic Spinel Ferrite Nanoparticles: From Synthesis to Biomedical Applications

“…Silica is often used as a coating and encapsulating material to form a core-shell inorganic nanocomposite. Silica can significantly improve the colloidal and chemical stability, facilitate surface functionalization and reduce toxicity [80]. Thus, magnetite NPs were obtained by co-precipitation, stabilized by coating agents, and encapsulated in hollow-shell mesoporous silica NPs (Fe3O4@MSN) with the aim of drug loading and drug delivery application, as shown in Fig.…”

Design and Development of Gold-Loaded and Boron-Attached Multicore Manganese Ferrite Nanoparticles as a Potential Agent in Biomedical Applications

“…One option to overcome this restraint would be to place multiple magnetic cores on a larger substrate such as silica or an organic layer, resulting in an increase in the total magnetic content per particle and an improvement in high colloidal stability. 16 , 17 In addition to being an MRI agent, MnFe 2 O 4 nanoparticles have been recognized as a magnetic hyperthermia tool in cancer therapy due to the generation of heat under a magnetic field and drug carrier. 18 …”

“…Compared to iron oxide nanoparticles, manganese ferrite nanoparticles (MnFe 2 O 4 ) are commonly used as T 2 contrast agents and possess high saturation magnetization and excellent T 2 -negative contrast because they can be shown to be more efficient at promoting transverse relaxivity ( r 2 ). − Although the r 2 values can be increased by increasing the size of the individual particles, this causes some difficulties, such as large and mononuclear magnetic nanoparticles tend to be polydisperse and agglomerated in suspension. One option to overcome this restraint would be to place multiple magnetic cores on a larger substrate such as silica or an organic layer, resulting in an increase in the total magnetic content per particle and an improvement in high colloidal stability. , In addition to being an MRI agent, MnFe 2 O 4 nanoparticles have been recognized as a magnetic hyperthermia tool in cancer therapy due to the generation of heat under a magnetic field and drug carrier …”

“…One option to overcome this restraint would be to place multiple magnetic cores on a larger substrate such as silica or an organic layer, resulting in an increase in the total magnetic content per particle and an improvement in high colloidal stability. 16,17 In addition to being an MRI agent, MnFe 2 O 4 nanoparticles have been recognized as a magnetic hyperthermia tool in cancer therapy due to the generation of heat under a magnetic field and drug carrier. 18 PTT is a highly specific and minimally invasive cancer treatment method depending on the killing of cancer cells by achieving sufficient hyperthermia under laser irradiation compared to the traditional cancer treatment methods such as chemotherapy and radiotherapy.…”