Current and Future Applications of Monoclonal Antibodies against Bacteria in Veterinary Medicine

Sherman, David M.; Markham, Robert

doi:10.1016/b978-0-12-463003-1.50018-6

Cited by 3 publications

(2 citation statements)

References 96 publications

(97 reference statements)

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“…MoAbs againsl Escherichia coli. administered orally into newborn calves before inoculation with bacteria, do cause a significant decrease in diarrhoea and morlalily rate [26].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial action of antibodies against Giardia muris trophozoites

Belosevic

Faubert

Dharampaul

1994

Clinical and Experimental Immunology

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The activities of immune serum and trophozoite-specific MoAb were examined in vitro and in vivo. Immune serum and anti-Giardia muris MoAb caused immobilization of the trophozoites in vitro and were cytotoxic for trophozoites in the presence of exogenous complement. Both immune serum obtained from experimentally infected mice and anti-G. muris MoAb administered directly into the duodenum of mice significantly reduced the number of trophozoites in the small intestine during the acute phase of the infection. These results suggest that serum antibodies play a central role in the elimination of the primary Giardia infection.

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“…MoAbs againsl Escherichia coli. administered orally into newborn calves before inoculation with bacteria, do cause a significant decrease in diarrhoea and morlalily rate [26].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial action of antibodies against Giardia muris trophozoites

Belosevic

Faubert

Dharampaul

1994

Clinical and Experimental Immunology

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“…The therapeutic and prophylactic prospects for human mAb have been reviewed recently (Larrick and Bourla, 1986) and all these ideas are potentially applicable to veterinary problems (Sherman and Markham, 1986). Perhaps the major limitation to development along these lines is the cost/benefit ratio.…”

Section: Applications and Potentialmentioning

confidence: 99%

The production and application of non-rodent monoclonal antibodies in veterinary science

Groves

Tucker

1989

Veterinary Immunology and Immunopathology

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The requirement for monoclonal antibodies derived from species other than rats and mice is becoming increasingly realised in veterinary, as well as human, medicine. This paper reviews current knowledge of the production of inter-species hybridomas (heterohybridomas) by the fusion of rodent myeloma cell lines with lymphocytes from species of veterinary importance. To date a number of monoclonal immunoglobulins derived from sheep, cattle, pig, rabbit, mink and primate species have been produced to a variety of different bacterial, viral and nematode pathogens as well as to blood group and MHC determinants and to hormones. The technique opens up a number of possibilities for the future; some of these applications are discussed in relation to the antibodies produced thus far.

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Production and Use of Bovine and Ovine Monoclonal Antibodies

Groves

Morris

1988

Clinical Applications of Monoclonal Antibodies

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Current and Future Applications of Monoclonal Antibodies against Bacteria in Veterinary Medicine

Cited by 3 publications

References 96 publications

Antimicrobial action of antibodies against Giardia muris trophozoites

Antimicrobial action of antibodies against Giardia muris trophozoites

The production and application of non-rodent monoclonal antibodies in veterinary science

Production and Use of Bovine and Ovine Monoclonal Antibodies

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