Current and Future Economic Burden of Osteoporosis in New Zealand

Brown, Paul; McNeill, R; Leung, William; Radwan, Eman; Willingale, Jane

doi:10.2165/11531500-000000000-00000

Cited by 33 publications

(17 citation statements)

References 25 publications

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“…Although the majority of burden of illness studies only reported the costs associated with osteoporosis-related hospitalizations [32, 34–36], non-acute care accounted for almost 50% of our base case direct cost estimates, which was higher than estimates reported in the US (38%) [37], Germany (33%) [30], and New Zealand (33%) [31]. Differences in the cost categories included in the non-acute care calculations may explain these variations (e.g., home care and long-term care).…”

Section: Discussionmentioning

confidence: 92%

The burden of illness of osteoporosis in Canada

et al. 2012

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SummaryTo update the 1993 burden of illness of osteoporosis in Canada, administrative and community data were used to calculate the 2010 costs of osteoporosis at $2.3 billion in Canada or 1.3% of Canada’s healthcare expenditures. Prevention of fractures in high-risk individuals is key to decrease the financial burden of osteoporosis.IntroductionSince the 1996 publication of the burden of osteoporosis in 1993 in Canada, the population has aged and the management of osteoporosis has changed. The study purpose was to estimate the current burden of illness due to osteoporosis in Canadians aged 50 and over.MethodsAnalyses were conducted using five national administrative databases from the Canadian Institute for Health Information for the fiscal-year ending March 31 2008 (FY 2007/2008). Gaps in national data were supplemented by provincial and community data extrapolated to national levels. Osteoporosis-related fractures were identified using a combination of most responsible diagnosis at discharge and intervention codes. Fractures associated with severe trauma codes were excluded. Costs, expressed in 2010 dollars, were calculated for osteoporosis-related hospitalizations, emergency care, same day surgeries, rehabilitation, continuing care, homecare, long-term care, prescription drugs, physician visits, and productivity losses. Sensitivity analyses were conducted to measure the impact on the results of key assumptions.ResultsOsteoporosis-related fractures were responsible for 57,413 acute care admissions and 832,594 hospitalized days in FY 2007/2008. Acute care costs were estimated at $1.2 billion. When outpatient care, prescription drugs, and indirect costs were added, the overall yearly cost of osteoporosis was over $2.3 billion for the base case analysis and as much as $3.9 billion if a proportion of Canadians were assumed to be living in long-term care facilities due to osteoporosis.ConclusionsOsteoporosis is a chronic disease that affects a large segment of the adult population and results in a substantial economic burden to the Canadian society.

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Section: Discussionmentioning

confidence: 92%

The burden of illness of osteoporosis in Canada

et al. 2012

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“…When investigating, e.g. hip fractures, other studies have shown results within the range of EUR 15,500–50,000 when converted to 2011 prices by consumer price index (for European countries, harmonized indices of consumer prices in health care have been used) [6, 14, 15, 41, 42]. This study showed that the estimated cost of hip fractures was EUR 13,683 for men and EUR 9,385 for women, which also included productivity cost.…”

Section: Discussionmentioning

confidence: 99%

“…The complete societal burden of osteoporotic fractures should therefore also include quality of life, as this is an important aspect of patients' well-being. COI studies from Sweden [6, 9], New Zealand [41] and Germany [43] show that osteoporosis and osteoporotic fractures impose a significant loss in quality of life. Thus, it must be expected that similar findings would be found for the Danish population.…”

Section: Discussionmentioning

confidence: 99%

A health economic analysis of osteoporotic fractures: who carries the burden?

et al. 2013

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SummaryThis is a cost-of-illness study of osteoporotic fractures in Denmark estimating the incremental societal cost associated with osteoporotic fractures, with both direct cost and productivity cost. This study includes cost regarding hospitals, general practices, the patients, the municipalities and regions. The total cost of osteoporotic fractures in Denmark was estimated at EUR 1.563 billion.PurposeThe aim of this study is to estimate the societal burden imposed by osteoporotic fractures in Denmark. In contrast to prior studies, this study will present a comprehensive model for the cost of osteoporotic fractures regarding hospitals, general practices, the municipalities, the regions and the patients.MethodsThis cost-of-illness study applied an incidence-based bottom-up approach from a societal perspective, including both direct costs and productivity costs. The study focused on incremental cost associated with osteoporotic fractures using a Markov model. Danish citizens ≥50 years with an osteoporotic fracture between 2001 and 2010 were studied.ResultsThe total cost of osteoporotic fractures in Denmark was estimated to EUR 1.563 billion in 2011, at EUR 628 million and EUR 936 million for men and women, respectively. The most expensive fracture for both genders was first hip fracture. The municipalities carried the majority of the costs, with 55–57 % of incremental lifetime cost.ConclusionsThis study showed that the incremental societal burden of osteoporotic fractures is an important health problem. Medical costs of the osteoporotic fractures were substantial cost for the health care sector, but were by far exceeded by the cost for the municipality in terms of social services and rehabilitation.Electronic supplementary materialThe online version of this article (doi:10.1007/s11657-013-0126-3) contains supplementary material, which is available to authorized users.

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“…It is a global problem seen most often in the elderly and in women (80%) [1] and is considered one of the ten most important diseases affecting the world’s population [2] and is particularly prevalent in developed countries with ageing populations and longer life spans [3]. Bone loss is accelerated at early menopause resulting in increasingly fragile bones prone to breakage.…”

Section: Introductionmentioning

confidence: 99%

“…The number of older (> 50 years) New Zealanders is increasing steadily and the cost of treating fractures and secondary illnesses related to osteoporosis is expected to rise from $330 million in 2007 to $458 million by 2020 [3]. …”

Section: Introductionmentioning

confidence: 99%

Midlife women, bone health, vegetables, herbs and fruit study. The Scarborough Fair study protocol

2013

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BackgroundBone loss is accelerated in middle aged women but increased fruit/vegetable intake positively affects bone health by provision of micronutrients essential for bone formation, buffer precursors which reduce acid load and phytochemicals affecting inflammation and oxidative stress. Animal studies demonstrated bone resorption inhibiting properties of specific vegetables, fruit and herbs a decade ago.Objective: To increase fruit/vegetable intake in post menopausal women to 9 servings/day using a food specific approach to significantly reduce dietary acid load and include specific vegetables, fruit and herbs with bone resorbing inhibiting properties to assess effect on bone turnover, metabolic and inflammatory markers.Methods/DesignThe Scarborough Fair Study is a randomised active comparator controlled multi centre trial. It aimed to increase fruit and vegetable intake in 100 post menopausal women from ≤ 5 servings/day to ≥ 9 servings/day for 3 months. The women in the dietary intervention were randomly assigned to one of the two arms of the study. Both groups consumed ≥ 9 servings/day of fruit/vegetables and selected herbs but the diet of each group emphasised different fruit/vegetables/herbs with one group (B) selecting from a range of vegetables, fruit and culinary herbs with bone resorbing inhibiting properties. 50 women formed a negative control group (Group C usual diet).Primary outcome variables were plasma bone markers assessed at baseline, 6 weeks and 12 weeks. Secondary outcome variables were plasma inflammation and metabolic markers and urinary electrolytes (calcium, magnesium, potassium and sodium) assessed at baseline and 12 weeks. Dietary intake and urine pH change also were outcome variables. The dietary change was calculated with 3 day diet diaries and a 24 hour recall. Intervention participants kept a twice weekly record of fruit, vegetable and herb intake and urine pH.DiscussionThis study will provide information on midlife women’s bone health and how a dietary intervention increasing fruit and vegetable/herb intake affects bone, inflammatory and metabolic markers and urinary electrolyte excretion. It assesses changes in nutrient intake, estimated dietary acid load and sodium: potassium ratios. The study also explores whether specific fruit/vegetables and herbs with bone resorbing properties has an effect on bone markers.Trial registrationACTRN 12611000763943

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Current and Future Economic Burden of Osteoporosis in New Zealand

Abstract: Osteoporosis and osteoporotic fractures create a significant burden on the health system in New Zealand. This study highlights the significant scope of the burden of osteoporosis and the potential gains that might be made from introducing interventions to mitigate the burden.

Cited by 33 publications

References 25 publications

The burden of illness of osteoporosis in Canada

The burden of illness of osteoporosis in Canada

A health economic analysis of osteoporotic fractures: who carries the burden?

Midlife women, bone health, vegetables, herbs and fruit study. The Scarborough Fair study protocol

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