The article presents an analysis of the main mechanisms for regulating risks caused by the malicious use of artificial intelligence (MUAI) in the USA, the EU and China. The relevance of the MUAI problem is proven by numerous data on the use of artificial intelligence (AI) technologies by antisocial actors. The authors set a goal – to identify the specifics of regulating MUAI risks in the USA, EU and China – due to the innovative experience of these three jurisdictions. It was found that in the USA counteraction to MUAI has not yet been shaped into systemic decisions at the level of federal authorities. It is more about decisions that take into account the growing risks of MUAI within the framework of general regulation of AI and the safety of its use. The EU has adopted the world's first Law on AI, which however pays little attention to the MUAI issues, and the main initiators of proposals to counter and regulate risks are law enforcement agencies, such as Europol. In China, MUAI risk regulation is most centralized and is becoming the subject of strategic documents and legislative acts. The authors use a systemic approach when considering various options for MUAI threats and formulating the research conclusions.