Current aspects of high blood pressure research in Africa

Abstract

Hypertension in Africa represents a challenge and an opportunity. As the two epidemics of infection and malnutrition are increasingly brought under control, increasing morbidity and mortality from hypertension have been documented and offer a challenge for prevention. Heterogeneity within and between African populations offers opportunities for detecting clues to the etiology and pathogenesis of hypertension. For example, populations in urban areas have already shown a greater prevalence of obesity, hypertension, and hypertensive heart and kidney disease than those in rural areas. The generally better lipid profiles in African blacks compared with whites is associated not only with low rates of coronary heart disease, but also with low prevalences of hypertensive retinopathy, despite substantial prevalences of hypertension in African blacks. Areas of Africa with a natural abundance of salt, such as Gambia and Senegal, tend to have indigenes with less tendency to retain a salt load than those from areas that are traditionally salt poor.

An estimate of the prevalence of hypertension in Nigeria

“…This estimate is relatively comparable with the estimates reported for sub-Saharan Africa between 1981 and 2008 by Danaei et al [57], with an overall mean SBP ranging from 129.2 to 132.7 mmHg and 132.6 and 134.8 mmHg among men and women, respectively. This may broadly reflect an increasing overall mean blood pressure and a rising prevalence of hypertension in the country when compared to other world regions [58]. From the pooled crude prevalence rates, we observed that the prevalence of hypertension was higher among the urban dwellers than that observed among the rural dwellers (31 versus 26%).…”