Current Clinical Status of Lipid-Mobilizer Hormone

Abstract

A number of studies dealing with a lipidmobilizing hormone (LM)

Russell's diencephalic syndrome of early childhood

“…In leprechaunism the only report of HGH assay is an isolated measurement reported by Dekaban (1965) which is at the upper level of the normal fasting range (1-10 tlu/ml). The total lack of subcutaneous fat in Russell's diencephalic syndrome may be partly attributable to increased production of HGH, but the lipid mobilizing fraction (LM) isolated by Zarafonetis, Seifter, Baeder, and Kalas (1959) from the pituitary and the fat mobilizing polypeptide (FMS) isolated from urine by Chalmers, Pawan, and Kekwick (1960) may also play their part. These last two substances may be quite unrelated to HGH but Pawan (1971) suggests that FMS may in fact prove to be a degradation product of HGH.…”

The Diencephalic Syndrome of Infancy

“…Speech and gait improved and the tremor decreased. During the en¬ suing 12 Case 2.-A white male infant weighed 4.4 kg (9 lb 12 oz) when delivered after uncomplicated gestation. At 9 months of age he weighed 11.2 kg (25 lb) ; the mother was warned not to overfeed him.…”