Preliminary Studyt is usually difficult to detect hypopharyngeal carcinoma at an early stage because of inconspicuous pharyngeal symptoms. The patient often presents with advanced disease that has a poor prognosis. 1 Endoscopic and imaging examinations are considered indispensable approaches in diagnosis of hypopharyngeal carcinoma. Endoscopy can be used to directly observe a tumor arising from mucosa, on which biopsy can be performed. Additionally, its ability to show the laryngeal structure and movement is helpful for tumor staging. 2 However, it is difficult to determine the depth and extrahypopharyngeal invasion of advanced carcinoma, and it is frequently impossible to visualize the inferior part of a bulky lesion that obstructs passage of the endoscope. Xia, MD, Qiang Zhu, MD, Yun Cheng, MD, Han Xue Zhao, MD, Zhen Zhen Jin, MD Received July 20, 2010,
Chun Xia
ORIGINAL RESEARCHObjectives-This study investigated the ability of sonography for diagnosis of hypopharyngeal carcinoma.Methods-Between November 2008 and January 2010, 34 consecutive patients with hypopharyngeal carcinoma (34 tumors) were examined by sonography. The visualization capability of sonography was evaluated by grading criteria of "excellent," "good," "moderate," and "poor" in comparison with computed tomography (CT). Localization of the primary tumor foci and intrahypopharyngeal and extrahypopharyngeal invasion were initially assessed by sonography and confirmed with surgical and pathologic findings. Laryngeal movement was observed on real-time sonography and compared with endoscopic findings.Results-On sonography, 29 of the 34 lesions (85.3%) were graded excellent, similar to the shapes and dimensions of the tumors on CT. Localization was correctly undertaken in 26 of the 28 foci resected (92.9%), with excellent agreement between sonography and surgical and pathologic findings (κ = 0.823; P < .001). In evaluating intrahypopharyngeal and extrahypopharyngeal invasion with sonography, the sensitivity and specificity were 90.9% and 82.4%, respectively, for intrahypopharyngeal intersubsite spreading, 50.0% and 96.2% for diagnosis of thyroid cartilage destruction, both 100% for evaluation of cervical esophagus, neck soft tissue, and thyroid gland involvement, and 76.9% and 100% for assessment of hemilarynx fixation.Conclusions-Sonography has a similar role in visualization of hypopharyngeal carcinoma as CT and is satisfactory in localization of the primary focus and assessment of tumor extension inside and outside the hypopharynx.