“…The literature also contains reports describing how the tissue holding capacity (Ingle et al, 2004) and the in vivo biostability of barbed sutures (Leung, 2004) depends on the microstructure of the polymer from which they are made. Currently they are used successfully for sub-dermal wound closure and for tendon repair in human patients (O'Broin et al, 1993;McKenzie, 1967), and by cosmetic surgeons to undertake facelift and masklift procedures (Prado et al, 2008;Michael et al, 2008;Downs and Wang, 2008;Ruff, 2006).…”