“…Patients with hepatitis C with cryoglobulinemia may present with positive rheumatoid factor; therefore, consider potential hepatitis C risk factors. Patients with tickborne illnesses, Rocky Mountain spotted fever, or Lyme disease can present with joint pain, but frequently demonstrate a characteristic rash, fever, and history of tick bite 9,10. In patients with an oligo- or monoarthritic presentation, the diagnosis would be more likely due to crystalline arthropathies (such as gout or pseudogout), septic arthritis, or spondyloarthropathies associated with human leukocyte antigen (HLA)-B27 9…”