CURRENT DIAGNOSTIC BRONCHOSCOPY FOR EARLY CENTRAL LUNG CANCER (Review of literature)

Соколов, В. В.; Соколов, Д. В.; Пирогов, С. С.; Каприн, А. Д.; Рябов, А. Б.; Волченко, Н. Н.; Кудрявцева, Ю. Л.; Strunina, Alena

doi:10.21518/2079-701x-2016-15-62-66

Cited by 4 publications

(2 citation statements)

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“…Зуйков 1 , И.А. Попова 1 1 Челябинский областной клинический центр онкологии и ядерной медицины, Челябинск, Российская Федерация; 2 Южно-Уральский государственный медицинский университет, Челябинск, Российская Федерация АННОТАЦИЯ Обоснование. Проблема диагностики и лечения злокачественных новообразований лёгких является крайне актуальной.…”

Section: повышение качества диагностики и верификации периферических ...unclassified

“…Каждый год в мире выявляется более 1 млн новых случаев рака лёгкого [1,2]. Также необходимо отметить, что, по данным международного агентства по изучению рака, злокачественные новообразования данной локализации ежегодно являются наиболее частой причиной смертности во всём мире [1].…”

Section: Improving the Quality Of Diagnosis And Verification Of Perip...unclassified

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Improving the quality of diagnosis and verification of peripheral lung neoplasms by using a modified biopsy technique for ultrasonic bronchoscopy (EBUS)

Pushkarev

Важенин²,

Кулаев³

et al. 2022

Russian Journal of Oncology

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BACKGROUND: The problem of diagnosis and treatment of malignant neoplasms of the lungs is extremely relevant. Verification of the malignant process in the case of peripheral localization of the neoplasm in the lung when using ultrasound bronchoscopy does not exceed 70.6%. AIMS: This study aimed to improve the effectiveness of ultrasound bronchoscopy in the State Medical Institution Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine by introducing into clinical practice a modified biopsy technique for ultrasound bronchoscopy. The technique is patented, patent for invention no. RU2719666 C1. MATERIALS AND METHODS: From 2019 to 2021, a study was conducted based on the endoscopic department of the State Medical Institution Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine, which included 137 patients. The patients were divided into two groups: the main group included 66 patients in whose examination FBS with endoussis with biopsy by a modified technique was used; the comparison group included 71 patients who underwent ultrasound bronchoscopy with biopsy by a standard technique. The time of biopsy manipulation according to the standard procedure ranged from 14 to 41 min, averaging 305 min. Ultrasound bronchoscopy with biopsy by a modified technique lasted from 16 to 45 minutes, on average 315 min. RESULTS: In the main group, where FBS with ENDOUSSI with biopsy was used in the diagnosis of patients using a modified technique with endosonographic control of the position of the endoscopic instrument in the pathological focus, the diagnosis of malignant neoplasm was verified in 52 patients (in 78.8% of cases). In the comparison group, where the standard biopsy technique was used in patients with ultrasound bronchoscopy, the diagnosis of malignant neoplasm was verified in 41 patients (in 57.7% of cases). Thus, the verification of peripheral lung malignancies when using a modified biopsy technique increases by 21.1% (p 0.05). FBS with endoussis with biopsy using a modified technique is satisfactorily tolerated by patients and is a relatively safe manipulation. CONCLUSION: modified biopsy technique developed by us with endosonographic control of the position of the endoscopic instrument in the pathological focus during ultrasound bronchoscopy makes it possible to increase the percentage of verification of peripheral lung malignancies by 21.1% (p 0.05). The introduction and widespread use of the modified biopsy technique for ultrasound bronchoscopy in the diagnosis of peripheral lung malignancies will reduce the time of examination of patients and prescribe antitumor treatment earlier.

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Section: повышение качества диагностики и верификации периферических ...unclassified

Section: Improving the Quality Of Diagnosis And Verification Of Perip...unclassified

Improving the quality of diagnosis and verification of peripheral lung neoplasms by using a modified biopsy technique for ultrasonic bronchoscopy (EBUS)

Pushkarev

Важенин²,

Кулаев³

et al. 2022

Russian Journal of Oncology

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Application of video-assisted thoracoscopic lung resections for differential diagnosis of lung diseases

Самородов¹,

Сабанчиева

Vasilev

2021

Tuberk. bolezni lëgk.

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The objective of the study: to determine the place and effectiveness of video-assisted thoracoscopic lung resection (VATS resections) in the differential diagnostic procedure for examination of patients with chest diseases.Subjects and methods. In 2017-2019, 1,190 patients with suspected respiratory tuberculosis were examined in the differential diagnostic department of TB Dispensary, the Ministry of Health of the Kabardino-Balkarian Republic; 106 (8.9%) needed VATS since it was impossible to verify their diagnosis despite various biopsies. The age of 106 patients varied from 18 to 80 years old, there were 66 men (62.0%), and 40 women (38.0%). The preoperative diagnosis was as follows: single or multiple lung lesions – 83 (76.9%) cases, disseminated lung disease of unknown etiology or interstitial lung disease of unspecified etiology – 25 (23.1%) cases.In all cases, the surgical specimens were sent for comprehensive tests, including histological tests, microbiological tests (fluorescent microscopy with Ziehl-Nielsen staining, culture for Mycobacterium tuberculosis (MTB) by Bactec, and culture for secondary flora and fungi), and molecular genetic tests to detect MTB DNA.Results. The diagnostic efficiency when using VATS resections, histological and microbiological testing of surgical specimens made 98.1% (95% CI 93.38-99.48; Wilson's method). Among the diagnosed diseases, pulmonary tuberculosis was confirmed in 47/106 (44.3%) patients, cancer – 37/106 (34.9%), the rest of patients were diagnosed with some other disorders including orphan diseases.

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Modified Biopsy Assessment for Endobronchial Ultrasound in Diagnosis of Peripheral Lung Neoplasms

Pushkarev

Важенин

Кулаев

et al. 2022

Kreativnaâ hirurgiâ i onkologiâ

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Background. Diagnosis and treatment of malignant lung neoplasms are pressing issues. Peripheral lung cancer verification rate with endobronchial ultrasound varies within 30–85 %.Aim. To advance endobronchial ultrasound precision, a modified biopsy technique has been developed and introduced into clinical practice at the Chelyabinsk Regional Clinical Centre for Oncology and Nuclear Medicine. The modification comprises real-time ultrasound image guidance of the biopsy forceps alignment and opening. The technique patent for invention is RU 2719666 C1.Materials and methods. Modified endobronchial ultrasound has been performed in 66 patients with suspected peripheral lung malignancy at the Centre’s Department of Endoscopy within 2019–2021. Bioptic material was delivered for histological and, when necessary, immunohistochemical examination.Results. Malignancy diagnosis was verified in 78.8 % cases. The modified technique is relatively safe, with complications detected in two patients (3.8 % cases) and managed conservatively with success. Discussion. The standard biopsy technique provided for a lung malignancy verification rate of 57.7 % over 2019–2021. Thus, the rate improvement by modified technique is 21.1 %. The modified technique is relatively safe, with complications reported in two patients (3.8 % cases) and managed conservatively with success. Modified endobronchial ultrasound was adequately tolerated, with no increase in patient examination time. The technique can supersede more invasive diagnostic procedures.Conclusion. We believe that the modified technique will improve the power of endobronchial ultrasound, reduce examination time and expedite prescription of special therapies.

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CURRENT DIAGNOSTIC BRONCHOSCOPY FOR EARLY CENTRAL LUNG CANCER (Review of literature)

Cited by 4 publications

References 5 publications

Improving the quality of diagnosis and verification of peripheral lung neoplasms by using a modified biopsy technique for ultrasonic bronchoscopy (EBUS)

Improving the quality of diagnosis and verification of peripheral lung neoplasms by using a modified biopsy technique for ultrasonic bronchoscopy (EBUS)

Application of video-assisted thoracoscopic lung resections for differential diagnosis of lung diseases

Modified Biopsy Assessment for Endobronchial Ultrasound in Diagnosis of Peripheral Lung Neoplasms

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