Current epidemiological trends of brain abscess: a clinicopathological study

Singh, Neha; Singh, Deepak Kumar; Kumar, Rakesh; Prajapati, Hanuman Prasad

doi:10.1515/romneu-2017-0067

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…Most of the pa ents were in first three decades of life ie; 21(70%). This finding was in 16 congruence with most other studies like Singh et al (2017) 17 18…”

Section: Discussionsupporting

confidence: 93%

Profile of Patients with Brain Abscess

Khatiwada

Bista

Jha

et al. 2020

Birat J. Health Sci.

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Introduction: Despite of the advent of modern neurosurgical techniques and antibiotics, brain abscess possesses a major neurosurgical challenge in treatment. In this study we present the profile , clinical features , radiological features , treatment received and their outcome of cases of brain abscess that we managed in our center. Methods: Total 30 patients diagnosed with brain abscess who underwent treatment in last four months were included in this study. A descriptive observational data of brain abscess and the outcome variables in the form of Glasgow Outcome Scale (GOS) at discharge , hospital stay, and mortality were studied. The ultimate outcome was measured in Glasgow Outcome Score. Results: Total number of cases was 30, outwith male dominance 19 (63.3%) . Age ranged from 2 months to 60 years. Twenty-five patients were of acute pyogenic abscess while and rest were tubercular abscess. Common clinical features were headache (70%), fever (30%), vomiting (23%), seizure (23%) and focal neurological deficits (16.7%). Overall mean hospital stay was 31 days. The common aetogenic factors included chronic suppurative otitis media (16.7%), tuberculosis (16.7%), post-traumatic (10%), congenital heart disease (10%) and rest (46%) were of unknown source. lobe Temporal lobe and cerebellar were most common site involved (20%) each followed by frontal (16.7%). Surgery was done in 25 (83.3%) cases out of which 12 underwent burr hole and aspiration and 12 patients underwent craniotomy and excision and one patient underwent burr hole and followed by craniotomy. Five patients were managed conservatively. Complete resolution of abscess with complete recovery of preoperative neurological-deficit was seen n 28 (93.3%) cases. Conclusion: Early diagnosis and timely intervention improves the outcome of brain abscess. Most of the cases required surgical intervention and drainage of pus and had good postoperative outcome.

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“…Most of the pa ents were in first three decades of life ie; 21(70%). This finding was in 16 congruence with most other studies like Singh et al (2017) 17 18…”

Section: Discussionsupporting

confidence: 93%

Profile of Patients with Brain Abscess

Khatiwada

Bista

Jha

et al. 2020

Birat J. Health Sci.

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“…There were 70% men (data not reported in 3 studies) and the mean age of patients was 40.3 years (data not reported in 5 studies). The cases were distributed as follows: 9 from India [4,8,9,11,[13][14][15][16][17], 4 from Taiwan [18][19][20][21], 3 from Spain [12,22,23], 3 from France [7,24,25], 2 from UK [26,27], and one each from USA [28], Italy [29], Finland [30], Hungary [10], South Africa [31], Denmark [3] and Pakistan [32].…”

Section: General Characteristicsmentioning

confidence: 99%

Brain abscesses caused by anaerobic microorganisms: a systematic review

Cobo¹

2023

Rev Esp Quimioter

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The objective of this study was to perform a systematic review of the characteristics, causative microorganisms and outcome of brain abscesses caused by anaerobic bacteria over the past 25 years. We reviewed studies on brain abscesses which included infection due to anaerobic microorganisms published between 1998 and 2022. We excluded reports with polymicrobial infections (more than 2 anaerobic bacteria isolated) and those that do not provide enough information to make comparisons, the reports with only one case of brain abscess due to anaerobes, as well as those focused on an only anaerobic bacterium. Also, we have excluded the cases in pediatric population. We searched the scientific literature through the Cochrane Library, EMBASE and PubMed/MEDLINE databases for studies of this condition. We finally included 28 studies with 6,167 patients, of which 715 (11.5%) were cases caused by anaerobic bacteria. There was a male predominance (70%) and mean age of 40.3 years. Most infections were monomicrobial (59.4%). The most common anaerobic microorganisms isolated were Bacteroides spp (43.4%) and Gram-positive anaerobic cocci (35.1%). Cases of brain abscesses caused by anaerobic bacteria were most frequent in Asia and Europe. The source of infection most frequent was otogenic in 84.6% followed by a neurosurgery procedure infection in 23% of patients. The main symptom observed was headache in 95.6% of patients followed by fever (69.5%). Surgical treatment was performed in 48 % of patients and the percentage of patients in whom antibiotic treatment was applied range 88.8% to 100%. The main limitation of this review is the non-inclusion of studies published before of 1998 in which MALDI-TOF MS system had not been introduced in the majority of laboratories for routine identification. The patient rate with isolation of anaerobic bacteria in brain abscesses is low, but these data could be underestimated mainly due to the fastidious nature of these microorganisms and the difficulties in the identification of some anaerobes.

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Anaerobic bacteriological profile of brain abscess in a tertiary care center in southern India

Shruthi

Raj

et al. 2019

Anaerobe

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Current epidemiological trends of brain abscess: a clinicopathological study

Cited by 3 publications

References 9 publications

Profile of Patients with Brain Abscess

Profile of Patients with Brain Abscess

Brain abscesses caused by anaerobic microorganisms: a systematic review

Anaerobic bacteriological profile of brain abscess in a tertiary care center in southern India

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