2021
DOI: 10.1080/17474124.2021.1991792
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Current epidemiology in hepatocellular carcinoma

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Cited by 168 publications
(89 citation statements)
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“…For patients with type 2 diabetes and metabolic syndrome, weight loss and regular aerobic exercise can reduce insulin resistance and improve inflammation [ 68 ]. In China, overweight and obesity increased by 414% between 1982 and 2002, which may contribute to NAFLD becoming an increasingly common cause of HCC in Asia [ 69 ]. Although lifestyle factors are strongly associated with NAFLD and an association with HCC has been demonstrated in animal studies, data on the relationship between humans and HCC are scarce.…”
Section: Prevention Methods Of Hcc In Asiamentioning
confidence: 99%
“…For patients with type 2 diabetes and metabolic syndrome, weight loss and regular aerobic exercise can reduce insulin resistance and improve inflammation [ 68 ]. In China, overweight and obesity increased by 414% between 1982 and 2002, which may contribute to NAFLD becoming an increasingly common cause of HCC in Asia [ 69 ]. Although lifestyle factors are strongly associated with NAFLD and an association with HCC has been demonstrated in animal studies, data on the relationship between humans and HCC are scarce.…”
Section: Prevention Methods Of Hcc In Asiamentioning
confidence: 99%
“…According to data from the Surveillance, Epidemiology, and End Results (SEER) program, HCC has been the fastest-growing cause of mortality due to cancer in the United States since the early 2,000s and is projected to become a leading cause of cancer death by 2030 without intervention ( Rahib et al, 2014 ). HCC is most commonly a sequel of chronic liver disease caused by chronic viral hepatitis, alcohol-induced injury, non-alcoholic fatty liver disease, exposure to aflatoxin B1, and several metabolic diseases ( Singal et al, 2020 ; Konyn et al, 2021 ). Treatment modalities include resection, ablation, chemoembolization, or liver transplant ( Forner et al, 2019 ; Yarchoan et al, 2019 ).…”
Section: Introductionmentioning
confidence: 99%
“…Hepatocellular carcinoma (HCC) accounts for 75–85% of primary liver cancers [ 1 ]. Several risk factors, such as hepatitis B or C virus infection, aflatoxin exposure, smoking, and heavy alcohol intake contribute to HCC development [ 2 ]. HCC has a high mortality rate owing to its late diagnosis, frequent recurrence, and drug resistance.…”
Section: Introductionmentioning
confidence: 99%