Current knowledge of small cell lung cancer transformation from non-small cell lung cancer

Pt–Se-Bonded Nanoprobe for High-Fidelity Detection of Non-small Cell Lung Cancer and Enhancement of NIR II Photothermal Therapy

“…However, these techniques often present operational difficulties and are limited by their high costs. 6,7 Calcium-activated neutral protease 2 (CAPN2) is a calcium-dependent cysteine protease that plays a crucial role in angiogenesis, cell proliferation, and migration. Abnormal expression of CAPN2 has been observed in NSCLC, establishing it as a significant biomarker for NSCLC.…”

“…Lung cancer is one of the most common types of cancer worldwide, which can be primarily classified into two types based on the distinct growth patterns of tumor cells: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). , NSCLC accounts for 85% of cases and is difficult to detect and diagnose in the early stages due to its slower growth and proliferation, as well as the lack of obvious warning signs. − Currently, common diagnostic methods for lung cancer include computed tomography, magnetic resonance imaging, and histopathological analysis. However, these techniques often present operational difficulties and are limited by their high costs. , Calcium-activated neutral protease 2 (CAPN2) is a calcium-dependent cysteine protease that plays a crucial role in angiogenesis, cell proliferation, and migration. Abnormal expression of CAPN2 has been observed in NSCLC, establishing it as a significant biomarker for NSCLC .…”

The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer

“…From a histopathological perspective, lung cancer has two major classifications: small and non‐small cell lung cancers (SCLC and NSCLC, respectively). The latter accounts for around 85% of all lung cancer cases, with a 5‐year overall survival (OS) rate of about 15% 6–8 . Thus, it is of particular importance to identify more critical factors influencing the treatment efficacy of NSCLC.…”

“…The latter accounts for around 85% of all lung cancer cases, with a 5-year overall survival (OS) rate of about 15%. [6][7][8] Thus, it is of particular importance to identify more critical factors influencing the treatment efficacy of NSCLC.…”

Dual-targets fluorescent nanoprobe for precise subtyping of lung cancer

“…Lung cancer is a highly heterogeneous disease with distinct clinical characteristics, 1,2 which can be categorized into non-small cell lung cancer (NSCLC), representing 85% of cases, and small cell lung cancer (SCLC), representing 15%. 3,4 These two types of lung cancer have different etiologies and clinical features, necessitating different treatment approaches for patients. Currently, lung cancer detection methods include computer tomography (CT), magnetic resonance imaging (MRI), and biopsy.…”