1995
DOI: 10.1001/archsurg.1995.01430020084016
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Current Management and Long-term Prognosis of Hepatolithiasis

Abstract: Improvement of stone clearance rate is evident by a systematic approach. Complete relief from calculi, bile stasis, and cholangitis at an early stage of the disease is mandatory to prevent progressive liver damage, because repeated recurrence of intrahepatic calculi and cholangitis ultimately lead to irreversible liver damage and hepatobiliary carcinomas with a high mortality.

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Cited by 79 publications
(35 citation statements)
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“…The association between cholangiocarcinoma and RPC is well recognized, and the incidence of cholangiocarcinoma in patients with hepatolithiasis at the time of hepatic resection ranges from 2.4% to 23.3%. 18,21,23,[29][30][31][32] None of the patients in the present series had cholangiocarcinoma at the time of primary surgery. Only one patient developed cholangiocarcinoma in the follow up period.…”
mentioning
confidence: 61%
“…The association between cholangiocarcinoma and RPC is well recognized, and the incidence of cholangiocarcinoma in patients with hepatolithiasis at the time of hepatic resection ranges from 2.4% to 23.3%. 18,21,23,[29][30][31][32] None of the patients in the present series had cholangiocarcinoma at the time of primary surgery. Only one patient developed cholangiocarcinoma in the follow up period.…”
mentioning
confidence: 61%
“…However, the decision for surgical resection was based on the symptomatic hepatolithiasis. The indications for hepatectomy for hepatolithiasis are as follows: Hepatolithiasis in the unilateral lobe, severe stricture or dilatation of the biliary duct, hepatolithiasis associated with intrahepatic bile duct carcinoma, accompanied by formation of hepatic abscesses or atrophy of the liver (11,12). The radiological findings mimicked those of intrahepatic cholangiocarcinoma; however, repeated cytology of the bile juice revealed no malignancy.…”
Section: Discussionmentioning
confidence: 99%
“…The hepatic resections are combined with high morbidity and mortality rate. The recurrence of cholangitis caused by high residual stone rate and high recurrent stone seriously affect therapeutic effect [8,9]. Documents reported that surgery mortality was 5.24%, residual stone rate was 30.7%, and reoperation rate was up to 37.1 to 74%.…”
Section: Discussionmentioning
confidence: 99%