Current Management of Urinary Tract Infection in Children

Kïbar, Yusuf

doi:10.5772/23280

Cited by 6 publications

(7 citation statements)

References 96 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Boys are more susceptible during the first year of life, mostly the first 3 months; thereafter the incidence is substantially higher in girls ( 2 ). Among boys, uncircumcised infants have an eightfold higher risk ( 3 ). About 5% of girls and 2% of boys experience at least one episode of UTI up to the age of seven years ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

“…Effective management of patients suffering from severe UTI commonly relies on the identification of pathogenic organisms and the selection of an effective antibiotic agent to the organism in question. However, diagnosis of UTI is often delayed due to obscure clinical findings, particularly in infants and children of less than tow years ( 2 , 3 , 6 ). Moreover, it is difficult to collect urine and interpret the results to confirm the diagnosis unequivocally in this age group ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

“…However, diagnosis of UTI is often delayed due to obscure clinical findings, particularly in infants and children of less than tow years ( 2 , 3 , 6 ). Moreover, it is difficult to collect urine and interpret the results to confirm the diagnosis unequivocally in this age group ( 3 ). Hence, empirical antibiotic prescription is often endorsed even without culture and sensitivity.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pediatric urinary tract infection as a cause of outpatient clinic visits in southern Ethiopia: a cross sectional study

Mitiku¹,

Amsalu²,

Tadesse³

2018

Ethiop J Health Sci

View full text Add to dashboard Cite

BackgroundFailure to timely diagnose and treat urinary tract infections is associated with grave long term consequences. The objectives of this study included assessing the proportion and predictors of Urinary Tract Infection (UTI) as a cause of pediatric outpatient department (OPD) visits and determining common uropathogens with antimicrobial susceptibility pattern.MethodsA cross sectional study was conducted from May to September 2015 among children of less than 15 years old at a tertiary center in Hawassa, Ethiopia. Children who fulfilled predefined eligibility criteria were recruited to undergo urine culture and urine analysis.ResultsA total of 863 children visited the OPD during the study period among which 269(31.2%) fulfilled the predefined eligibility criteria. Urine culture was positive for 74/269(27.5%) of the clinically suspected children. Male uncircumcision (adjusted odds ratio (aOR) 3.70; 95% CI 1.34–10.16) and under nutrition (aOR 5.41; 95%CI 2.64–11.07) were independent predictors of culture positivity. More than 5 WBC per high power field (aOR 4.7, 95% CI 1.8–12.7) on microscopy, urine PH > 5.0 (aOR 2.6, 95%CI 1.2–5.8), and positive leukocyte esterase (aOR 9.9, 95%CI 4.1–25.7) independently predicted positive growth on urine culture. Escherichia coli (34/74, 45.9%) and Klebsiella spp (18/74, 24.3%) were the most frequent isolates. High resistance was noted against amoxicillin (70.6%) and cotrimoxazole (97.1%) by E. coli.ConclusionUTI accounted for a tenth of total OPD visits. Commonly used first line antibiotics showed high level resistance to common etiologies of UTI. UTI should be suspected in febrile children, and antibiograms should be done to tailor prescription of antibiotics.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pediatric urinary tract infection as a cause of outpatient clinic visits in southern Ethiopia: a cross sectional study

Mitiku¹,

Amsalu²,

Tadesse³

2018

Ethiop J Health Sci

View full text Add to dashboard Cite

show abstract

“…According to Shahian et al [21], even moderate dehydration in jaundiced infants can result in the presence of WBC in their urine. Pyuria is not a sensitive marker for detecting UTIs in jaundiced infants, and it may result in an overestimation of UTI cases [36].…”

Section: Discussionmentioning

confidence: 99%

Prediction of Urinary Tract Infection in Neonates with Unexplained Indirect Hyperbilirubinemia

Abdelrheem

Aly

Diab

et al. 2022

Open Access Maced J Med Sci

View full text Add to dashboard Cite

Background: Neonates with urinary tract infection (UTI) are susceptible to higher rates of morbidity and mortality, specifically when presented with hyperbilirubinemia. Screening for UTIs in jaundiced neonates is a cost-effective strategy. The aims of this study were to investigate the pattern of UTI (prevalence, etiology, and susceptible antimicrobial agents) in neonates admitted to the NICU with unexplained indirect hyperbilirubinemia, as well as to identify early predictors of UTI in order to reduce the present morbidity and long-term consequences in NICU patients. . Methods: A cross-sectional hospital-based study that included 140 neonates diagnosed with unexplained indirect hyperbilirubinemia in the first 4 weeks of life. A questionnaire was applied to obtain demographic and clinical data. A number of laboratory parameters were assessed with clinical examination. Bacterial growth of 1 × 103 colony-forming units/mL of a single uropathogen was used to identify the existence of UTI. Multivariate analysis was used to identify the predicting factors of UTIs. Results: In the NICU group investigated, 25.7% of subjects had a culture-proved UTI. The most frequently isolated organism was Escherichia coli. Amikacin was the most common antibiotic that the isolates were susceptible to. In multivariable logistic regression analysis, a positive urine culture was statistically associated with an increase in WBCs (OR= 6.90, p= 0.001), pyuria (OR= 5.55, p= 0.001), small for gestational age (OR= 4.07, p= 0.021), prolonged phototherapy duration (OR= 3.50, p= 0.034), and the presence of obstetric complications (OR= 2.92, p= 0.001). Conclusion: UTI is substantially prevalent among neonates admitted to the NICU with unexplained indirect hyperbilirubinemia. The importance of routine UTI screening (urine culture) as part of the clinical assessment of unexplained hyperbilirubinemia was highlighted in this study, particularly in neonates with leukocytosis, pyuria, small for gestational age, prolonged phototherapy, and those born from mothers with a history of obstetric complications.

show abstract

“…Renal parenchymal infection and scarring are well-established complications of UTI in children and can lead to renal insufficiency, hypertension and renal failure. Although frequently encountered and well researched, diagnosis and management of UTI continue to be a controversial issue with many challenges for the clinician [1].…”

Section: Introductionmentioning

confidence: 99%

Developments Regarding Dysfunctional Voiding and Urinary Tract Infections in Children

Kïbar¹,

Gök²

2013

Recent Advances in the Field of Urinary Tract Infections

Self Cite

View full text Add to dashboard Cite

Additional information is available at the end of the chapter . IntroductionUrinary tract infection UTI is the most commonly diagnosed bacterial infections of childhood, and have a significant healthcare impact. Renal parenchymal infection and scarring are well-established complications of UTI in children and can lead to renal insufficiency, hypertension and renal failure. "lthough frequently encountered and well researched, diagnosis and management of UTI continue to be a controversial issue with many challenges for the clinician [ ].Dysfunctional voiding DV imposes a considerable social, developmental and physical burden on children and their families. Children that suffer from DV generally present with complaints of UTI, incontinence, constipation and voiding symptoms such as urinary urgency and frequency. Vesicoureteral reflux VUR may also be present in some children with more severe DV, possibly resulting in hydronephrosis, pyelonephritis and even secondary chronic renal insufficiency [ ].The true estimate of DV in the general population is not known. Reported population estimates of DV are based on questionable methodology. " wide variation from . -. % has been reported depending on the definition used and the methodology adopted [ , ]. It is probable that these figures represent a gross overestimate of the actual prevalence. In tertiary care centres, DV constitutes up to % of referrals in the Paediatric Urology department [ , ]. This chapter will focus on the epidemiology, diagnosis and management of DV and UTI in neurologically and anatomically normal children. The discussion will highlight recent developments and research in the clinical approach of DV and UTI.

show abstract

Current Management of Urinary Tract Infection in Children

Cited by 6 publications

References 96 publications

Pediatric urinary tract infection as a cause of outpatient clinic visits in southern Ethiopia: a cross sectional study

Pediatric urinary tract infection as a cause of outpatient clinic visits in southern Ethiopia: a cross sectional study

Prediction of Urinary Tract Infection in Neonates with Unexplained Indirect Hyperbilirubinemia

Developments Regarding Dysfunctional Voiding and Urinary Tract Infections in Children

Contact Info

Product

Resources

About