Corporate social responsibility (CSR), as a business concept that balances between economic, environmental, and social goals of a company, is usually seen as a good response to all mentioned challenges. Since the theory on CSR still does not prove an unambiguous conclusion on the role and importance of CSR for business success in developing economies, there is a need of investigating this concept and the level of its implementation. The main aim of this chapter is to investigate the concept of CSR, the level of its implementation, and the organizational-level predictors of CSR practice. The methodology is based on the analysis of the sample of 151 large private companies in Serbia. The authors used a specially designed questionnaire, based on the standardized ones, with respect to the context of Serbia, as a developing economy, in order to get responses on CSR. The single-respondent methodology was used, too. The data analysis is carried on in the SPSS program. The main conclusions, implications, and limitations of the research are given at the end of the chapter.