Current production of bioherbicides: mechanisms of action and technical and scientific challenges to improve food and environmental security

Bordin, Eduarda Roberta; Camargo, Aline Frumi; Stefanski, Fábio Spitza; Scapini, Thamarys; Bonatto, Charline; Zanivan, Jessica; Preczeski, Karina Paula; Modkovski, Tatiani Andressa; Júnior, Francisco Wilson Reichert; Mossi, Altemir José; Fongaro, Gislaine; Ramsdorf, Wanessa Algarte; Treichel, Helen

doi:10.1080/10242422.2020.1833864

Cited by 27 publications

(14 citation statements)

References 86 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Another problem that needs to be solved for the effective use of BCHs is the selection or development of NP formulations [ 172 , 181 ]. For the initial evaluation of BCHs, the simplest formulations are usually tested.…”

Section: Perspectives Of Natural Compounds As Biorational Herbicidesmentioning

confidence: 99%

Modern Approaches for the Development of New Herbicides Based on Natural Compounds

Berestetskiy

2023

Plants

View full text Add to dashboard Cite

Weeds are a permanent component of anthropogenic ecosystems. They require strict control to avoid the accumulation of their long-lasting seeds in the soil. With high crop infestation, many elements of crop production technologies (fertilization, productive varieties, growth stimulators, etc.) turn out to be practically meaningless due to high yield losses. Intensive use of chemical herbicides (CHs) has led to undesirable consequences: contamination of soil and wastewater, accumulation of their residues in the crop, and the emergence of CH-resistant populations of weeds. In this regard, the development of environmentally friendly CHs with new mechanisms of action is relevant. The natural phytotoxins of plant or microbial origin may be explored directly in herbicidal formulations (biorational CHs) or indirectly as scaffolds for nature-derived CHs. This review considers (1) the main current trends in the development of CHs that may be important for the enhancement of biorational herbicides; (2) the advances in the development and practical application of natural compounds for weed control; (3) the use of phytotoxins as prototypes of synthetic herbicides. Some modern approaches, such as computational methods of virtual screening and design of herbicidal molecules, development of modern formulations, and determination of molecular targets, are stressed as crucial to make the exploration of natural compounds more effective.

show abstract

Section: Perspectives Of Natural Compounds As Biorational Herbicidesmentioning

confidence: 99%

Modern Approaches for the Development of New Herbicides Based on Natural Compounds

Berestetskiy

2023

Plants

View full text Add to dashboard Cite

show abstract

“…122 Some herbicide molecules produced by microorganisms may be toxic to humans and animals. 112 For example, the AAL toxin produced by the fungus Alternaria alternata is a potent herbicide against broadleaf weeds and acts on the sphingolipid metabolism, causing the plasma membrane to rupture, leading to cell death. 123 However, this toxin can also trigger cell death and neoplastic events in mammals.…”

Section: ■ Microbial-based Herbicidesmentioning

confidence: 99%

“…Naturally found in plants, soil, and aquatic environments, these molecules can serve as carbon and energy sources for microorganisms . Natural molecules exhibit lower toxicity toward nontarget organisms than conventional formulations. ,− In addition, formulations that ensure reliable soil management are indispensable to avoid problems with water and nutrient availability and, consequently, with crop health . For example, Adetunji et al isolated the metabolite 2-(hydroxymethyl) phenol extracted from the bacterium Pseudomonas aeruginosa C1501.…”

Section: Advantages and Limitations Of Using Bioherbicidesmentioning

confidence: 99%

Nature-Based Herbicides and Micro-/Nanotechnology Fostering Sustainable Agriculture

Campos

Ratko

Bidyarani

et al. 2023

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

Bioherbicides, also known as nature-based herbicides, play a crucial role in sustainable agriculture by effectively inhibiting weed growth and development. They help increase crop productivity by reducing competition between plants for nutrients, water, and light. Their eco-friendly nature sets bioherbicides apart, promoting environmentally conscious farming practices. Despite their numerous benefits, many bioherbicide compounds are inherently unstable and susceptible to environmental degradation by temperature, light, humidity, and microbial activity, thus posing challenges for effective weed management. To address this issue, a growing emphasis has been placed on encapsulation strategies in recent years. Encapsulation techniques offer several advantages for bioherbicides, including enhanced efficacy, sustainable biological compound release, environmental factor protection, and shelf life improvement. Polymers, particularly biopolymers, are promising materials for bioherbicide encapsulation in micro-/nanoparticles. These particles are specifically designed for the targeted delivery of bioherbicides, ensuring effective crop protection and weed management. Micro-/nanotechnology incorporation in encapsulated formulation development has revealed their notable potential. This study focuses on the latest developments in the encapsulation of bioherbicides into micro-/nanoparticles and their practical application for weed management. By leveraging micro-/nanotechnology, researchers aim to maximize bioherbicidal application and efficacy, paving the way for sustainable agricultural weed management practices. The findings of this study may serve as a reference for expanding the use of micro-/nanotechnology-associated bioherbicides for providing potential sustainable weed control solutions.

show abstract

“…The selective nature of bioherbicides with rapid degradation properties deserves more attention than synthetic herbicides [24]. Interestingly, phytotoxins synthesized by various plants and microorganisms are excellent sources for weed control and could revolutionize sustainable agriculture [28,29]. Chen et al reported that even low concentrations of phytotoxins have a good inhibitory effect on weeds, which is an added advantage of developing bioherbicides [30].…”

Section: Introductionmentioning

confidence: 99%

Searching of Novel Herbicides for Paddy Field Weed Management—A Case Study with Acetyl-CoA Carboxylase

Antony

Ramanathan

2022

Agronomy

View full text Add to dashboard Cite

Weed management is the major biological constraint in paddy (Oryza sativa L.) producing areas. Predominantly, barnyard grass (Echinochloa crus-galli) is a rice-mimicking weed that causes 57% of yield loss in rice production. Conventionally, herbicides are the site-specific weed inhibitors often used to suppress E. crus-galli growth. Acetyl-CoA carboxylase (ACCase) is an important target for developing novel herbicides with remarkable selectivity against gramineous weeds. Notably, fenoxaprop-P-ethyl (FPPE) is a selective ACCase herbicide extensively used in paddy fields to inhibit barnyard grass. However, prolonged use of FPPE herbicide elicits phytotoxicity in cultivated rice and herbicide resistance in weeds. Recently, phytotoxins are emerging as an alternative to commercial herbicides with safer environmental profiles. Nevertheless, discovering natural herbicides through in vivo and in vitro techniques is time-consuming and expensive. Therefore, high-end computational screening strategies including Tanimoto similarity, docking, binding free energy, and herbicide-likeness were used to pinpoint the lead molecule. Finally, molecular dynamics and MM/PBSA calculations were employed to validate the binding kinetics of the hit compound. Indeed, sinigrin was identified as a promising phytotoxic inhibitor against the ACCase enzyme. The findings of our study were well correlated with the existing experimental results. Overall, the current work will aid in the development of commercializing phytotoxin herbicides in foreseeable future.

show abstract

Current production of bioherbicides: mechanisms of action and technical and scientific challenges to improve food and environmental security

Cited by 27 publications

References 86 publications

Modern Approaches for the Development of New Herbicides Based on Natural Compounds

Modern Approaches for the Development of New Herbicides Based on Natural Compounds

Nature-Based Herbicides and Micro-/Nanotechnology Fostering Sustainable Agriculture

Searching of Novel Herbicides for Paddy Field Weed Management—A Case Study with Acetyl-CoA Carboxylase

Contact Info

Product

Resources

About