2024
DOI: 10.3390/vaccines12050533
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Current Progress in Vaccines against Merkel Cell Carcinoma: A Narrative Review and Update

Thilo Gambichler,
David Schrama,
Riina Käpynen
et al.

Abstract: Merkel cell carcinoma is a rare, aggressive skin cancer that mainly occurs in elderly and immunocompromised patients. Due to the success of immune checkpoint inhibition in MCC, the importance of immunotherapy and vaccines in MCC has increased in recent years. In this article, we aim to present the current progress and perspectives in the development of vaccines for this disease. Here, we summarize and discuss the current literature and ongoing clinical trials investigating vaccines against MCC. We identified 1… Show more

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