2024
DOI: 10.1002/adfm.202408386
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Current Progress on Scale‐Up and Commercialization of Microbially‐Produced Silk

David N. Breslauer

Abstract: Over the past two decades, significant advancements have been made in the scalable production and commercialization of microbially‐produced recombinant protein polymers. This perspective presents the evolution from early research efforts to the development of market‐ready products, with a focus on recombinant silk‐like proteins. Initial attempts to synthesize spider silk proteins in microbial hosts faced challenges with solubility, stability, and yield. Recent advancements in synthetic biology, protein enginee… Show more

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