Despite a growing body of recent evidence on the hierarchical organization of the selfsimilar energy-containing motions in the form of Townsend’s attached eddies in wallbounded turbulent flows, their role in turbulent skin-friction generation is currently known very little. In this paper, the contribution of each of these self-similar energycontaining motions to turbulent skin friction is explored up to Reτ ≃ 4000. Three different approaches are employed to quantify the skin-friction generation by the motions, the spanwise length scale of which is smaller than a given cut-off wavelength: 1) FIK identity in combination with the spanwise wavenumber spectra of the Reynolds shear stress; 2) confinement of the spanwise computational domain; 3) artificial damping of the motions to be examined. The near-wall motions are found to continuously lose their role in skin-friction generation on increasing the Reynolds number, consistent with the previous finding at low Reynolds numbers. The largest structures given in the form of very-large-scale and large-scale motions are also found to be of limited importance: due to a non-trivial scale-interaction process, their complete removal yields only 5 ∼ 8% of skin-friction reduction at all the Reynolds numbers considered, although they are found to be responsible for 20 ∼ 30% of total skin friction at Reτ ≃ 2000. Application of all the three approaches consistently reveals that the largest amount of skin friction is generated by the self-similar motions populating the logarithmic region. It is further shown that the contribution of these motions to turbulent skin friction gradually increases with the Reynolds number, and that these coherent structures are eventually responsible for most of turbulent skin-friction generation at sufficiently high Reynolds numbers