Current State of Cell Therapies for Breast Cancer

Gautam, Namrata; Elleson, Kelly; Ramya, G.; Czerniecki, Brian J.

doi:10.1097/ppo.0000000000000607

Cited by 12 publications

(3 citation statements)

References 111 publications

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“…It is advisable to visit a healthcare expert before deciding to utilize these therapies, considering the potential advantages and disadvantages for each patient. This is a continuously evolving field of study, with ongoing efforts to find novel treatments that enhance results and minimize adverse reactions [70,71,72].…”

Section: Discussionmentioning

confidence: 99%

Exploring the Efficacy of Targeted Therapies in Breast Cancer: A Comprehensive Review

Abdulatip,

Adorable,

Agosila

et al. 2023

Int. J. Res. Publ. Rev.

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This article delves into the various treatments accessible for patients who are severely ill. It centers on how these remedies can assist in understanding the workings of breast cancer specifically. By utilizing such therapies, individuals learn to regulate their bodily reactions while cultivating beneficial practices and adjusting their mindset towards more favorable results. Although cancer patients initially show reluctance towards therapy to handle their mental health concerns related to critical illness, researchers believe that genetics in combination with environmental factors often lead to the emergence of Breast Cancer from various sources including behavioral aspects. This leads to an increased risk manyfold over time due to certain hormone-catalyzed courses impacting individual behaviors. As it is one of the most frequently witnessed kinds worldwide and responsible for 12.5% of malignancy cases projected by year-end 2023, developing Breast Cancer remains primarily associated with being female whereby women are more vulnerable compared to counterparts' male healthcare population-supporting one out of four cancers carried by them.The incidence rate has progressively increased globally since its spurt nearly two decades ago, especially in localized-stage Hormone-receptor-positive diseases amounting to major causal elements. Despite positivity, decreasing death rates started showing itself at the 1989 peak trending slowly & stably downwards with a higher reduction trend around the preceding decade (1.5% vs 1/93%). Improvement seen can be attributed solely to enhanced medical interventions which have been dramatically successful over the years saving at least 390,000 individuals' lives at least.The main objective currently gears toward targeting woman hormones promoting cell growth in an inbound inexhaustible quantity than males. Today claims without sufficient certainty -no proven prevention or treatment exists such as breast removal surgery as a definitive solution for women with heightened likelihoods of conjoining factually effective therapeutic procedures medically administered. Lessons learned from this research could be utilized to make patient lifelong comfort better by boosting survival rates using improved treatment methods available today.

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Section: Discussionmentioning

confidence: 99%

Exploring the Efficacy of Targeted Therapies in Breast Cancer: A Comprehensive Review

Abdulatip,

Adorable,

Agosila

et al. 2023

Int. J. Res. Publ. Rev.

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“…Frontiers in Pharmacology frontiersin.org immunotherapy have led to longer survival, some patients with advanced breast cancer develop metastatic cancer (Gautam et al, 2022;Karn et al, 2022). Furthermore, the development and research of novel drugs to control metastasis remain a great challenge.…”

Section: Figurementioning

confidence: 99%

“…Triple-negative breast cancer is highly malignant and difficult to treat ( Hacking et al, 2022 ; Montalvo-Castro and Salinas-Jazmín, 2022 ). Although chemotherapy, radiation therapy, and systemic immunotherapy have led to longer survival, some patients with advanced breast cancer develop metastatic cancer ( Gautam et al, 2022 ; Karn et al, 2022 ). Furthermore, the development and research of novel drugs to control metastasis remain a great challenge.…”

Section: Salvianolic Acid Bmentioning

confidence: 99%

Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

Guo

Wang

2022

Front. Pharmacol.

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Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an important natural product derived from Salvia miltiorrhiza and this review summarizes the anticancer activity of Sal-B. Sal-B inhibits tumor growth and metastasis by targeting multiple cell signaling pathways. This review aims to review experimental studies to describe the possible anticancer mechanisms of Sal-B and confirm its potential as a therapeutic drug.

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