Current state of COVID-19 in children: 4 years on

Powell, Annabel A.; Dowell, Alexander C.; Moss, Paul; Ladhani, Shamez N.

doi:10.1016/j.jinf.2024.106134

Cited by 3 publications

References 104 publications

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The effect of COVID-19 vaccination on symptomatic infection and related symptoms among preterm-born children aged 3–7 years in China

Wang,

Ning,

Cao

et al. 2024

Sci Rep

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Vaccination plays a crucial role in preventing and controlling SARS-CoV-2 infections as well as their associated adverse outcomes. But there is a notable lack of research on the effectiveness of COVID-19 vaccination in children, particularly those young preterm-born children, who are more vulnerable to severe outcomes from SARS-CoV-2 infection. We aimed to determine the effect of vaccination with inactivated vaccines BBIBP-CorV and CoronaVac on symptomatic COVID-19 infection and related symptoms in preterm-born children aged 3-7 years after relaxation of the COVID-19 prevention and control measures in December 2022 in China. We performed a retrospective cohort study involving 242 preterm-born children aged 3-7 years and the data were collected in March 2023. Logistic regression models and modified Poisson regression models combined with entropy balancing were used to explore the associations of vaccination against SARS-CoV-2 with symptomatic COVID-19, specific symptoms, and persistent symptoms one month after recovery from COVID-19. Of the 242 recruited preterm-born children, 156 (64.5%) were vaccinated with inactivated vaccines BBIBP-CorV and CoronaVac. After entropy balancing, the covariates were balanced between the vaccinated and the unvaccinated groups, with standardized mean difference < 0.001. Vaccination with the said SARS-CoV-2 vaccines lowered the risk of developing symptomatic COVID-19 in preterm-born children (risk ratio [RR] = 0.783; 95% confidence interval [CI]: (0.711, 0.861). Likewise, COVID-19 vaccination was associated with a decline in the risk of pneumonia (odds ratio [OR] = 0.318; 95% CI 0.110, 0.913), fever (RR = 0.710; 95% CI 0.635, 0.794), high fever (RR = 0.542; 95% CI 0.297, 0.988), sore throat (OR = 0.304; 95% CI 0.139, 0.664), and persistent symptoms (RR = 0.425; 95% CI 0.182, 0.993). Immunization with inactivated vaccines BBIBP-CorV and CoronaVac provides protection against symptomatic COVID-19 for preterm-born children 3-7 years.

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The effect of COVID-19 vaccination on symptomatic infection and related symptoms among preterm-born children aged 3–7 years in China

Wang,

Ning,

Cao

et al. 2024

Sci Rep

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Perspective Chapter: Sequelae and Consequences of COVID-19 in the Paediatric Population

Manuel Gutiérrez-Gómez,

Ortiz-Ortega,

X. Pasco-Velázquez

et al. 2024

Current Topics in Post-Covid Syndromes [Working Title]

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During the pandemic and in subsequent years, we observed that COVID-19 caused by the SARS-CoV-2 virus affected the paediatric population in different ways. In certain groups of children and adolescents, social isolation, changes in family dynamics, increased exposure to technological screens and changes in diet, among others, have affected their development, education, emotional, physical and social aspects, including access to immunizations, medical surveillance and medical control. COVID-19 is considered a generally benign pathology in children; however, some patients develop well-defined post-COVID-19 entities: multisystem inflammatory syndrome in children (MIS-C) and long COVID. In this chapter, we review, in relation to the paediatric population, the effects of the pandemic and confinement during its development and its subsequent consequences, the forms of clinical presentation of COVID-19 and post-COVID-19 entities and MIS-C and long COVID, including prevalence, pathophysiology, presentation, evolution, detection and management recommendations.

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Changes in the Health Status of Children and Adolescents Before, During, and After the COVID-19 Pandemic: Focus on the Results of Health Examination

Choi,

Kim,

Park

et al. 2024

JKPHN

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Current state of COVID-19 in children: 4 years on

Cited by 3 publications

References 104 publications

The effect of COVID-19 vaccination on symptomatic infection and related symptoms among preterm-born children aged 3–7 years in China

The effect of COVID-19 vaccination on symptomatic infection and related symptoms among preterm-born children aged 3–7 years in China

Perspective Chapter: Sequelae and Consequences of COVID-19 in the Paediatric Population

Changes in the Health Status of Children and Adolescents Before, During, and After the COVID-19 Pandemic: Focus on the Results of Health Examination

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