In order to deal with the shortage of spacecraft telemetry, tracking, and command (TT&C) resources and the high complexity of planning and scheduling in the future, based on the current situation of the TT&C network in China, the construction requirements of space–ground integration TT&C network are put forward, and the basic framework is constructed. Referring to the random access mechanism of ground cellular mobile communication system, access once encountered TT&C mode is designed. This work introduces its basic idea, gives an example of the implementation process in the new form, designs the protocol stack system of random access TT&C, and probes into the key technologies, such as spacecraft access optimization selection strategy and panoramic (airspace) multi-beam and multi-target simultaneous TT&C technology, for reference of further research.