Background Health care services during a pregnancy and after delivery are important for the survival and well being of both the mother and the infant. The World Health Organization recommends a minimum of four antenatal care visits during a pregnancy. In Ethiopia, only 38% of women aged 15-49 with a live birth received at least one-time antenatal care visits from a skilled provider. This value is much more below the average rates of least developed countries and Sub-Saharan Africa. This study aimed to identify the determinant factor of antenatal care service visits among pregnant women in EthiopiaMethod The national-level cross-sectional Ethiopian Demographic and Health 2016 survey data were accessed and used for the analysis. A total of 7913 pregnant women were included in the study. Zero-inflated Poisson regression models were employed to identify the determinant of antenatal care visits.Results Only 35.5% of the pregnant mothers have visited at least four times and 64.5% of the pregnant mothers have visited less than four times during their periods of pregnancy. The study revealed that rich women (IRR 1.077, 95% CI: 1.029,1.127), having access to mass media (IRR=1.086, 95% CI: 1.045, 1.128), having pregnancy complications (IRR=1.203, 95% CI: 1.165, 1.242), secondary or above-educated women (IRR=1.112, 95% CI:1.052, 1.176), husband's having secondary or above level of education (IRR=1.085, 95% CI: 1.031, 1.142), being married (IRR = 1.187; 95% CI: 1.087,1.296) and women age >30 years (IRR=1.067, 95% CI: 1.024, 1.111) were strongly positively associated with the antenatal care visit. Rural pregnant women less antenatal visits (IRR=0.884, 95% CI: 0.846, 0.924) had also a statistically significant association with antenatal care visits.Conclusion This study was revealed rural women, poor women, uneducated mothers, uneducated husbands, not having access to mass media, unmarried women, have not pregnancy a complication was significantly associated with less number of antenatal care visit. Therefore, efforts are needed to advance the socioeconomic status of women, increasing the educational level of women and their husbands. The concerned body also should be made maternal health-care programs should be stretched and intensified in rural areas.