Current status of endemic goiter in Croatia: The results of a nationwide study (1995)

Kusić, Zvonko; Đaković, Nikola; Kaić-Rak, Antoinette; Karner, Ivan; Lechpammer, Stanislav; Mesaroš-Šimunčić, Elika; Petrović, Ivan; Rončević, Sanja; Smoje, Juraj; Staničić, Ante; Valent, I; Delange, François

doi:10.1007/bf03349869

Cited by 5 publications

(1 citation statement)

References 5 publications

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“…In each thyroid lobe a long and short axis US scan were used, as to obtain the length, width and depth in centimeters. Gland volume was fitted as a sum of lobe volumes [13,14]. The lobe volume was calculated using the rotation ellipsoid model formula [15,16].…”

Section: Techniquementioning

confidence: 99%

Effects of body weight, height, and body mass index on thyroid volume among healthy undergraduate Saudi males using ultrasound

Alsaqer¹,

Al-Kulaib²,

Alkhorayef³

et al. 2018

biomedicalresearch

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The aim of the current study was to correlate the effects of body weight, height, and body mass index (BMI) on thyroid volume of healthy undergraduate Saudi males by using ultrasound. After retaining an acceptance from the local ethics committee, a total of 100 (mean age was 21.8 ± 1.3 y; ages range from 18 to 22 y) participants were recruited between September 2016 and January 2018 in this prospective cohort study. Ultrasonographic measurements of the gland were performed using a HI vision Avius ultrasound unit (Hitachi), equipped with a high frequency direct contact 10 MHz linear array ultrasound probe. The calculated mean of thyroid volume was 7.5 ± 2.4 ml (right lobe volume was 3.9 ± 1.6 ml while that for left lobe was 3.6 ± 1.2 ml). Extremely statistically significant correlation (P<0.0001) was found between gland volume (ml) and participants' weight (kg), height (cm), and BMI (kg/m 2). In conclusion, the estimated thyroid volume was decreased significantly as participants' weight and BMI increase. In contrast, the volume increases significantly as height increases. Also, a local reference of thyroid volume among healthy undergraduate Saudi males was conducted.

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Section: Techniquementioning

confidence: 99%

Effects of body weight, height, and body mass index on thyroid volume among healthy undergraduate Saudi males using ultrasound

Alsaqer¹,

Al-Kulaib²,

Alkhorayef³

et al. 2018

biomedicalresearch

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First beneficial results of the implementation of Croatian new law on salt iodination

Kusić

Lechpammer

Lukinac

et al. 1999

J Endocrinol Invest

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Presented pilot-study on urinary iodine excretion among schoolchildren in main geographic regions of Croatia indicates a significant improvement in iodine excretion only 12 months after introduction of a new mandatory salt iodination with 25 mg KI/kg of salt. Measurements of urine iodine excretion in 663 schoolchildren of both sexes, aged 9-16 years, from Zagreb, Rude, Bednja, Osijek, Dakovo, Rijeka, Pazin and Dubrovnik showed that from 77.9% to 94.8% of subjects have had urinary iodine above 5 microg/dl. Also from 41.2% to 70.8% of children have had urinary iodine excretion above 10 microg/dl. Before introduction of a new law mostly borderline values of urinary iodine excretion were recorded; therefore recent values present significant positive shift and actually they are the best signs of almost adequate iodine intake in Croatian youth. Nevertheless, further measures for improvement of iodine intake are recommendable because still 31% of controlled table-salt samples from households and 15.7% of imported salt samples have had KI level below 20 mg/kg of NaCl. Salt produced in Croatia was (Pag and Nin salt plants) completely in accordance with iodination regulations. On the other hand, as recent increase in urinary iodine excretion could not be simultaneously followed by reduction in goiter prevalence, in the following years further epidemiological surveys of iodine deficiency disorders shall be warranted.

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Croatia has reached iodine sufficiency

Kusić

Novosel

Dabelić

et al. 2003

J Endocrinol Invest

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This study was performed in 2002, 6 yr after the introduction of a new regulation on salt iodination with 25 mg KI/kg of salt. The aim of the study was to evaluate whether further significant positive results of improved iodine intake could be observed among schoolchildren in Croatia. A total of 927 schoolchildren of both sexes, aged 6-12 yr, were included in the study. In Croatia, with a population of 4,437,460 the research was implemented in four major geographical regions: the Northwestern, Slavonia, Northern Adriatic and Dalmatian regions. Investigations included randomly selected pupils from regional centers and neighboring smaller towns or villages. The results have revealed that thyroid volumes were within the normal range according to the provisional WHO/ICCIDD reference values for sonographic thyroid volume in iodine-replete school-age children, updated in 2001. A significant improvement in medians of urinary iodine excretion was detected in 2002: from 9 microg/dl in 1991 to 14.6 microg/dl in Zagreb, from 4.3 microg/dl in 1995 to 13.1 microg/dl in Split, from 9.4 microg/dl in 1997 to 14.2 microg/dl in Rijeka and from 13.4 microg/dl in 1997 to 14.7 microg/dl in Osijek. An overall median of 14.0 microg/dl of urinary iodine excretion was detected in Croatian schoolchildren. The control of salt at different levels, from production to consumption, including salt produced in all three Croatian salt plants and imported salt, revealed that Croatian salt is adequately iodized. From severe iodine deficiency before the 1950s, through mild-to-moderate iodine deficiency in the 1990s, Croatia has now reached iodine sufficiency.

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Current status of endemic goiter in Croatia: The results of a nationwide study (1995)

Cited by 5 publications

References 5 publications

Effects of body weight, height, and body mass index on thyroid volume among healthy undergraduate Saudi males using ultrasound

Effects of body weight, height, and body mass index on thyroid volume among healthy undergraduate Saudi males using ultrasound

First beneficial results of the implementation of Croatian new law on salt iodination

Croatia has reached iodine sufficiency

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