Current status of <i>Humphreya endertii</i> and A new species (<i>Ganodermataceae</i>) recorded in south Vietnam

Two new lanostane triterpnenoids named endertiins A and B (1 and 2) together with two known compounds as ganodecalone A (3) and ergosterol (4) have been successfully isolated from the cultivated fruit bodies of the mushroom Humphreya endertii Stey (Ganodermataceae). Their structures were elucidated by a combination of HR-MS and 2D NMR spectroscopic analyses. In addition, endertiins A and B (1 and 2) were evaluated their cytotoxicity against two cancer cell lines, MCF7 (human breast carcinoma) and LU (human lung carcinoma). The result showed that endertiin A (1) could inhibit the growth of MCF-7 cells with its IC 50 value of 71.16 ± 6.25 g/ml.

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Endertiins A-B, two lanostane triterpenoids from the fruit bodies of the mushoom Humphreya endertii

Quang

Long

Tung

et al. 2020

Natural Product Research

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Current status of Humphreya endertii and A new species (Ganodermataceae) recorded in south Vietnam

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Endertiins A-B, two lanostane triterpenoids from the fruit bodies of the mushoom Humphreya endertii

Endertiins A-B, two lanostane triterpenoids from the fruit bodies of the mushoom Humphreya endertii

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