2023
DOI: 10.1007/s41252-023-00364-z
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Current Status of Psychopharmacological, Neuromodulation, and Oxytocin Treatments for Autism: Implications for Clinical Practice

Vicki Bitsika,
Christopher F. Sharpley

Abstract: Objectives To provide an overview of the current literature regarding the neurobiological treatments of psychopharmacology, neuromodulation, oxytocin therapy, and psychological resilience, as treatments for autism-related difficulties, and to distil the research findings from those treatments for everyday clinical application. Methods Instead of producing another specific systematic summary of the efficacy of these treatments, this review took an overview … Show more

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“…Presently, no approved pharmaceutical treatments exist for the core symptoms of ASD, and reported findings regarding the efficacy of OXT are inconsistent in both child and adult participants 107 . The shortcomings of clinical trials in OXT pharmacotherapy can be attributed to various factors, including a limited understanding of the biological basis of ASD, the absence of clinically meaningful markers to identify homogeneous patient subgroups, and the consequent absence of targeted therapeutic options 16 .…”
Section: Discussionmentioning
confidence: 99%
“…Presently, no approved pharmaceutical treatments exist for the core symptoms of ASD, and reported findings regarding the efficacy of OXT are inconsistent in both child and adult participants 107 . The shortcomings of clinical trials in OXT pharmacotherapy can be attributed to various factors, including a limited understanding of the biological basis of ASD, the absence of clinically meaningful markers to identify homogeneous patient subgroups, and the consequent absence of targeted therapeutic options 16 .…”
Section: Discussionmentioning
confidence: 99%