Study Need and Importance: The thulium fiber laser has emerged as an alternative laser lithotripsy technology to the gold standard, holmium:yttriumaluminum-garnet (Ho:YAG) laser. The SOLTIVEÔ SuperPulsed thulium fiber laser (SPTF) was the first platform released in North America and has shown promising clinical results in an adult cohort. No center has reported outcomes in a pediatric cohort. In this single-institution, retrospective cohort study, we aimed to compare the clinical performance of lowpower Ho:YAG lasers to the SPTF in matched, unilateral ureteroscopies performed in pediatric patients. What We Found: Over 5 years, 93 cases were performed with Ho:YAG lasers compared to 32 cases with the SPTF. The observed stone-free rate (SFR) with Ho:YAG lasers was 59% compared to 70% with the SPTF (see Table ). Use of the SPTF was associated with 61% lower odds of having a residual stone after ureteroscopy (95% CI: 0.19À0.77, p[0.01). Despite a significantly longer median laser time of 11 minutes with the SPTF compared to 2 minutes * Weighted logistic regression model.† Weighted linear regression model.