The use of three-dimensional/four-dimensional (3D/4D) ultrasound has become 'universalʼ in the increasingly precise diagnosis of fetal malformations. The introduction of new ultrasound modes, such as the HDlive or the Radiance System Architecture (RSA), which improve even more the quality of images, makes it easier to examine normal embryos and fetuses with incredible perfection and achieve diagnosis of malformations, increasingly complex and of high clinical importance.