Current Trend in Blood Transfusion Science, Where are we?

Uchejeso, Obeta M.

doi:10.23880/hij-16000159

Cited by 3 publications

(3 citation statements)

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“…Sensitization by a foreign antigen and subsequent exposure to the same antigen, respectively, result in alloimmunization and hemolytic transfusion responses (Erhabor et al, 2021;Haryani et al, 2017). The compatibility testing includes: ABO and Rhesus blood typing, antibody screening meant for the detection of unexpected antibodies and cross matching (Obeta et al, 2020).…”

Section: Compatibility Testingmentioning

confidence: 99%

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Blood Group System: Clinical Insight and Relevance in Medical Practice

Olanrewaju

Joy²,

Matthew

2023

EJHS

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Purpose: Thirty three blood group systems have recently received recognition from the International Society of Blood Transfusion. Numerous types of antigens have been found on the red cell membranes in addition to the ABO and Rhesus systems. One of the few significant tests that the anesthesiologist orders during the perioperative period is blood grouping and cross matching. To avoid difficulties associated with transfusions, it is crucial to have a thorough awareness of the blood group system, their clinical importance, typing and cross-matching tests and current implications. To explore the various blood group systems, their clinical significance, and their relevance in medical practice, including transfusion medicine, prenatal care and genetic testing Methodology: Relevant databases such as PubMed, Google Scholar and Scopus to search for literature related to blood group system were used for this study. Search strategy including keywords related to barium studies, cross-sectional imaging and low resource economies. This may include terms such as blood group system, ABO blood group, clinical significance, medical practice. Search terms in combination with Boolean operators (AND, OR, NOT) are used to retrieve relevant articles. Findings: Undoubtedly blood group systems is highly relevant in medical practice so as to prevent haemolytic transfusion reaction and alloimmunization of individual blood which can result to death of infants and other individuals. As beneficial as blood transfusion is blood group system of the donor and recipient must be identified to make the blood transfusion process safe. Blood group systems also gives clinical insights in medical practice which make disease diagnosis and treatment easier to approach. Recommendations: Health care providers should be trained to properly identify and type blood samples and blood banks should have appropriate quality control measures in place to ensure the accuracy of blood typing and cross matching. Healthcare providers involved in organ transplantation should be familiar with the blood group compatibility guidelines and communicate effectively with blood banks to ensure the availability of compatible donor organs.

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Section: Compatibility Testingmentioning

confidence: 99%

“…Therefore, accurate blood grouping or typing is crucial. Before transfusion, ABO typing is done by checking serum for the A and B antibodies and RBCs for the A and B antigens (Obeta et al, 2020). Rh typing is the next phase, and not more than 15% of the population is Rh-negative (Erhabor et al, 2021).…”

Section: Abo and Rhesus Blood Typingmentioning

confidence: 99%

Blood Group System: Clinical Insight and Relevance in Medical Practice

Olanrewaju

Joy²,

Matthew

2023

EJHS

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“…Latest Literature also suggests the association of various diseases with specific blood groups 1 .Studies have suggested the value of Computerized blood bank management information system in the accurate and smooth functioning of Blood Bank over the traditional system of manual method 2 .The Purview of Blood Bank can be extended by provision of facilities for storage of Cord Blood by employing new techniques 3 .Recent developments in Blood Grouping and Typing includes advancements in Molecular Typing ,and techniques such as Microarrays, Quartz Crystal microbalance and Lateral flow assays can minimize problems in grouping and typing 4 .The principles and practices of Blood Bank should abide by the Code of Ethics framed by International society of blood transfusion[ISBT] 5 .The role of Blood Bank has gone beyond the routine collection and dispensal of blood and its products to include special activities such as Apheresis and Stem cell collection ,Typing studies for HLA system, Cryopreservation and Infusion 6 . In recent times Autologous Blood Transfusion has proved to be safe and efficient alternative to routine blood transfusion ,as it can overcome many barriers associated with latter 17 .Plateletpheresis is of two types single donor platelet, random donor platelet .Single donor platelet is obtained directly from platelet pheresis machine and can raise platelet count by 30,000,whereas random donor platelet is prepared from whole blood by separation and can raise platelet count by 5000 for each unit respectively 18 .One unit of PRBC should raise haemoglobin by 1gm//dl and is indicated when haemohlobin is less than 6gm% 19 . Cryoprecipitate is a product of fresh frozen plasma which is thawed and sediment is collected, for use in severe bleeding, disseminated intravascular coagulation, as it is rich in factor 8 and fibrinogen, which raises fibrinogen by upto 10mg/dl 20 .Granulocyte concentrates are obtained from Apheresis machine and is indicated for short term in patients with severe infections with low granulocyte levels who are unresponsive to antibiotics of choice 21 .The type of transfusion related diseases detected in blood bank varies in accordance with region across the world.…”

Section: Introductionmentioning

confidence: 99%

Recent Trends and Practices in Blood Transfusion

Aggarwal

2024

ijmsdr

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Blood Transfusion is one of the most important, Potent and Critical therapeutic tools in the realm of Clinical Management of Patients. Modern Blood banking involves carefully coordinated sophisticated and integrated teamwork comprising of well experienced Technicians, Physicians along with the Donor/Patient support. It consists of latest Machinery and infrastructure to cater to the needs of patients, along with regular internal / external Audit, quality control and Calibration of Machines, which is vital to the efficient functioning of Blood Bank and delivery of smooth, accurate results. The aim of this study is to explore the various latest aspects of Blood Banking and reinforce the knowledge of Medical Community

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Pattern of Blood Transfusion in the Special Care Baby Unit of Benue State University Teaching Hospital in Makurdi North-Central Nigeria

Ochoga

Eseigbe

Onoja³

et al. 2021

J Res Bas Clin Sci

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Blood transfusion is a life-saving procedure in which whole blood or parts of blood are introduced into a patient's bloodstream intravenously. The need maybe due to physiological or pathological causes. The objective of this study was to document the pattern and indications for blood transfusion at the Special Care Baby Unit of the Benue State University Teaching Hospital (BSUTH), Makurdi. This study was a retrospective review of 126 neonates who received blood transfusion at the Special care baby unit of BSUTH from 1st January 2015 to 31st December 2019. Data was retrieved from patient's medical records and analyzed using IBM SPSS version 23. A total of 1142 neonates were admitted over the study period and 126 had blood transfusion giving a prevalence of 11.0%. Male/Female ratio of 1.57:1.Mean (±SD) Birth weight and gestational age (GA) were 2.23±0.82Kg and 35.48 ±3.95 weeks respectively. Exchange blood transfusion was the most frequent 53(42.1%) type of blood transfusion. The most common indications for blood transfusion were anaemia of prematurity, sepsis and severe neonatal jaundice. A hundred and twelve (88.9%) who received transfusion were discharged while 4(3.2%) died. The rate of blood transfusion was low, while severe neonatal jaundice and anaemia were the main indications for blood transfusion in this study. Exchange blood transfusion was the main type of transfusion.

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Current Trend in Blood Transfusion Science, Where are we?

Cited by 3 publications

References 0 publications

Blood Group System: Clinical Insight and Relevance in Medical Practice

Blood Group System: Clinical Insight and Relevance in Medical Practice

Recent Trends and Practices in Blood Transfusion

Pattern of Blood Transfusion in the Special Care Baby Unit of Benue State University Teaching Hospital in Makurdi North-Central Nigeria

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