Current Understanding of Alzheimer's Disease and Other Neurodegenerative Diseases, and the Potential Role of Diet and Lifestyle in Reducing the Risks of Alzheimer's Disease and Cognitive Decline

Brennan, Charles S.; Brennan, Margaret A.; Fernando, Warnakulasuriya Mary Ann Dipika Binosha; Martins, Ralph N.

doi:10.1002/9781119356752.ch1

Cited by 1 publication

(1 citation statement)

References 21 publications

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“…NDs are marked by the gradual loss of nerve cells, resulting in cognitive decline, memory loss, and reduced motor skills. Conditions like AD and dementia significantly challenge healthcare systems worldwide, prompting the need for new prevention and treatment methods [ 122 ]. NDs are also associated with early-stage gastrointestinal issues, such as constipation and delayed gastric emptying, alongside an imbalance in intestinal flora [ 123 ].…”

Section: Functional Fungal Polysaccharides and The Gut–brain Connecti...mentioning

confidence: 99%

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Barcan,

Vamanu

2024

JoF

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This review evaluates the therapeutic effects of polysaccharides derived from mushroom species that have medicinal and edible properties. The fungal polysaccharides were recently studied, focusing on their modulation of the gut microbiota and their impact on various diseases. The study covers both clinical and preclinical studies, detailing the results and highlighting the significant influence of these polysaccharides on gut microbiota modulation. It discusses the potential health benefits derived from incorporating these polysaccharides into the diet for managing chronic diseases such as diabetes, neurodegenerative disorders, and cancer. Furthermore, the review emphasizes the interaction between fungal polysaccharides and the gut microbiota, underscoring their role in modulating the gut microbial community. It presents a systematic analysis of the findings, demonstrating the substantial impact of fungal polysaccharides on gut microbiota composition and function, which may contribute to their therapeutic effects in various chronic conditions. We conclude that the modulation of the gut microbiota by these polysaccharides may play a crucial role in mediating their therapeutic effects, offering a promising avenue for further research and potential applications in disease prevention and treatment.

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Section: Functional Fungal Polysaccharides and The Gut–brain Connecti...mentioning

confidence: 99%

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Barcan,

Vamanu

2024

JoF

View full text Add to dashboard Cite

show abstract

Current Understanding of Alzheimer's Disease and Other Neurodegenerative Diseases, and the Potential Role of Diet and Lifestyle in Reducing the Risks of Alzheimer's Disease and Cognitive Decline

Cited by 1 publication

References 21 publications

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

Therapeutic Potential of Fungal Polysaccharides in Gut Microbiota Regulation: Implications for Diabetes, Neurodegeneration, and Oncology

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