Given a K3 surface X over a number field K, we prove that the set of primes of K where the geometric Picard rank jumps is infinite, assuming that X has everywhere potentially good reduction. The result is a special case of a more general one on exceptional classes for K3 type motives associated to GSpin Shimura varieties and several other applications are given. As a corollary, we give a new proof of the fact that X K has infinitely many rational curves.