Cushing's Syndrome in Childhood

doi:10.1016/s0140-6736(72)91696-0

The Lancet

1972

DOI: 10.1016/s0140-6736(72)91696-0

|View full text |Cite

Cushing's Syndrome in Childhood

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1975

1976

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Cushing's syndrome or obesity

Koelz

Girard

1976

Eur J Pediatr

View full text Add to dashboard Cite

A rare case of the Cushing syndrome, due to bilateral adrenal hyperplasia is described. Because of generalized obesity, normal height, normal bone age and family history of obesity, a boy 10 years of age had at first been misdiagnosed as simple obesity. A reduction in height velocity, advancement of bone age and development of precocious pseudopuberty led to a more detailed biochemical investigation and to the correct diagnosis. The clinical picture can be misleading in the differential diagnosis of Cushing's disease versus simple obesity. From a comparison of reports on pediatric Cushing's syndrome, it is obvious that in most pediatric cases fat distribution differs from that of adult Cushing's syndromes. Stunted growth is reported to be more frequent, but normal and excessive height in Cushing's syndrome is not uncommon. In adrenal hyperplasia a retardation of bone age is usually expected. Interpretation of endocrine functions must take into account that simple obesity leads to secondary endocrinopathies, which are similar to the findings in Cushing's syndromes. Plasma cortisol at midnight and 12 hourly excretion of free cortisol in urine as well as overnight Dexamethasone suppression of morning plasma cortisol are judged to be good screening parameters. Plasma ACTH assays can help in the initial diagnosis and are mandatory during the follow up for an early detection of Nelson's syndrome.

show abstract

Cushing's syndrome or obesity

Koelz

Girard

1976

Eur J Pediatr

View full text Add to dashboard Cite

show abstract

Short stature as the only clinical sign of Cushing's syndrome

Lee

Weldon

Migeon

1975

The Journal of Pediatrics

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Cushing's Syndrome in Childhood

Cited by 2 publications

References 22 publications

Cushing's syndrome or obesity

Cushing's syndrome or obesity

Short stature as the only clinical sign of Cushing's syndrome

Contact Info

Product

Resources

About