With the increasing awareness of environmental protection, Green Velvet Material (PLON), a renewable and environmentally friendly material, has been widely applied to mattresses. In order to improve the compressive properties of PLON, a series of experiments were carried out with special attention given to the compression deformation characteristics, support performance of the PLON blocks and its effective application in mattress products. The results are: (1) Average slopes of the load-deformation curves’ two phases are represented by K1 and K2, respectively. K1 is more sensitive to density changes that range from 30 kg/m3 to 50 kg/m3, while K2 is sensitive to density changes that range from 20 kg/m3 to 50 kg/m3. Their values increase with the rise of density; (2) 25% IFD, 40% IFD, 65% IFD, SF and IHF values are sensitive to density changes and they significantly increase with the rise of density. PLON blocks have excellent supporting properties and are considered to be comfortable according to American FPF Test Standard (ASTM-D3574-B1) when used in mattress bedding; (3) a PLON block density of 30 kg/m3 is preferentially selected for the softer type of mattress, while a PLON block density of 40 kg/m3 is preferentially selected for the harder type of mattress. The compression deformation characteristics and support performance of the PLON blocks were analyzed and the effective application of PLON in mattress products was explored through the above research.