The primary objective of this paper is to consider the influence of perceived usefulness, perceived ease of use, business innovativeness and product innovativeness on the adoption of mobile commerce. For the model of this study to be tested empirically, data were collected from mobile commerce users in Nigeria. A total of 405 questionnaires were used for the analysis via PLS-SEM. The results of the study revealed a positive and significant relationship between perceived usefulness, perceived ease of use, business innovativeness and product innovativeness. The results of this study provide some guides for mobile commerce practitioners.