SUMMARYObjective: This study analyses the role of ethnicity-based birth weight differences at term (37-42 weeks) between neonates of Roma and nonRoma populations in Hungary, controlling for socio-demographic and biological characteristics of the mothers.Methods: A cross-sectional survey among 9,040 mothers coupled with biometric data of the neonates was conducted in 2010. Inclusion criteria were: at term (37-42 weeks gestation) non-pathological pregnancies, and self-reported ethnicity. Birth weight was based on mothers' ethnicity, age, body mass index, education, marital and employment status, poverty level, household amenities, dietary and smoking habits using multiple linear regression.Results: The mean difference between Roma and non-Roma neonates measured without controlling for possible confounding factors was −288.7 gram (p < 0.001, 95% CI = −313.4-263.9). In the linear regression model Roma neonates weighed on average 69.67 grams less than nonRoma neonates (p < 0.001, 95% CI = 30.51-108.83). The mother's underweight BMI, low education and smoking during pregnancy (p < 0.001), age under 18 years, no amenities of housing and insufficient consumption of fruits and dairy products also significantly influenced (p < 0.05) the neonates' birth weight.Conclusion: Roma ethnicity was independently correlated with lower birth-weight among at term neonates, controlling for known risk factors. Roma ethnicity may serve as a proxy for other unmeasured social or biological factors and should be considered an important covariate for measurement among neonates.