Cut-off values of skeletal muscle index and psoas muscle index at L3 vertebra level by computerized tomography to assess low muscle mass

Bahat, Gülistan; Türkmen, Banu Özulu; Aliyev, Shamil; Çatıkkaş, Nezahat Müge; Bakir, Barış; Karan, Mehmet Akif

doi:10.1016/j.clnu.2021.01.010

Cited by 82 publications

(48 citation statements)

References 27 publications

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“…Thus, the EWGSOP2 recommended this topic as a high-priority study area. A study conducted by Bahat et al demonstrated that the psoas muscle index (PMI) cut-off values in the Turkish population differed from the cut-off values recommended by Prado et al [10].…”

Section: Introductionmentioning

confidence: 91%

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The Psoas Muscle Index and Retrospective Clinical Frailty Scale Score Predict Overall Survival in Patients With Multiple Myeloma

Koyuncu¹

2021

tjgeri

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Introduction: Using the retrospective Clinical Frailty Scale (CFS) to assess frailty and the psoas muscle index (PMI) to determine sarcopenia status are new concepts. Since the cut-off values of the PMI differ by race, populationspecific cut-offs are recommended. We aimed to investigate the prognostic significance of retrospective CFS scores and sarcopenia status determined by population-specific PMI cut-offs in patients with multiple myeloma (MM). Materials and Method:We included 111 patients who met the inclusion criteria. The patients' PMIs were calculated by measuring the psoas muscle at the level of the L3 vertebra on CT images. The CFS scores of the patients were retrospectively determined.Results: While 46 (41.4%) of the patients had sarcopenia, 79 (72%) were frail. The median follow-up duration was 21.7 (1.51-74.97) months. The median overall survival was 42.3 months. The risk of death was significantly higher in patients with sarcopenia than in patients without sarcopenia (log-rank p=0.028, HR: 2.43, 95% CI: 1.02-5.77), and frailty significantly affected overall survival (HR: 3.28, 95% CI: 1.28-8.41, p=0.01). Conclusion:Sarcopenia is a common finding in patients with MM. Both retrospective CFS scores and sarcopenia status, as determined by the PMI, were significantly associated with overall survival in patients with MM.

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Section: Introductionmentioning

confidence: 91%

“…The Hounsfield unit average calculation (HUAC) was obtained using the formula [(right mean psoas density × RPA) + (left mean psoas density x LPA)] / (RPA + LPA). A PMI <540 mm²/m² for men and <360 mm²/ m² for women were the cut-off points to define sarcopenia according to a Turkish population study [10].…”

Section: Ct Image Analysis and Sarcopenia Assessmentmentioning

confidence: 99%

The Psoas Muscle Index and Retrospective Clinical Frailty Scale Score Predict Overall Survival in Patients With Multiple Myeloma

Koyuncu¹

2021

tjgeri

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“…In Turkey, paracetamol is not commonly used for pain management due to its underappreciated analgesic effect in higher doses. The alcohol consumption rate is low between the ages of 18 and 60 in our country (7.8%) [19]. Also, between the ages of 65 and 74, the rate for men is 11.2% and 1.3% for women, while the rate is 4.4% for men and 0.5% for women aged 75 and over [20].…”

Section: • Paracetamolmentioning

confidence: 99%

Orthogeriatrics: a vital requirement for improving fragility fracture patient care internationally with particular reference to Turkey

et al. 2021

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Purpose Orthogeriatrics is a team approach that aims to provide adequate and timely intervention for individuals suffering from fragility fractures, particularly hip fractures. These patients are mostly the frailest older adults. The aim of orthogeriatrics is to re-gain functionality as early as possible and to decrease disability and mortality. Some developed countries have established orthogeriatric services, while many others, including Turkey, have so far not. Here, to identify areas for improvement, we outline the status of the orthogeriatrics in older adults in Turkey. Methods We present clear calls for action, emphasizing possible and noteworthy areas for improvement. Results Our proposals include the need for an easily applied, short version of comprehensive geriatric assessment; appropriate laboratory testing on admission; paracetamol with a special emphasis in its dosings and clues for state-of-the-art analgesic management; the essential need to introduce oral nutritional supplementation, irrespective of nutritional status; the need for vitamin D commencement, in almost all patients; and starting osteoporosis treatment in fracture hospitalization, whenever appropriate. Last but not least, the ever-increasing prerequisite to establish "fracture liaison services" is stipulated. Conclusion We suggest that our recommendations offer great potential in Turkey, for the improvement of frail fracture patients' care. We call the other countries that do not have established orthogeriatric lines to model our approach to improve the management of fracture patients globally. Keywords Orthogeriatrics • Improve • Care • Fragility fracture • Turkey Abbreviations ACS Acute coronary syndromes BCIS Bone cement implantation syndrome CGA Comprehensive geriatric assessment CKD Chronic kidney disease COPD Chronic obstructive pulmonary disease CRP C-reactive protein ECG Electrocardiogram FFFAP Falls and Fragility Fracture Audit Programme FIC Fascia iliaca compartment FLS Fracture Liaison Service

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“…Альтернативним місцем оцінки загальної м'язової маси є поперековий м'яз, який легко ідентифікується на КТ та може бути точно окреслений. У кількох дослідженнях встановлено, що зменшення нормалізованих до зросту товщини поперекового м'язу (Transversal Psoas Muscle Thickness, TPMT) та площі поперекового м'язу (Psoas Muscle Index, PMI) асоціюються з низьким виживанням хворих на рак та ЦП [1,3,12,13,15,28].…”

Section: вступunclassified

“…Сьогодні відсутній консенсус щодо референтних величин показників маси скелетної мускулатури. Це пов'язано з використанням різного програмного забезпечен- ня, залученням різних за основним захворюванням, віком, статтю та етнічною належністю пацієнтів [3,15,26]. Дані щодо референтних величин SMI, PMI та TPMT в українській популяції відсутні.…”

Section: вступunclassified

Diagnostic and prognostic value of psoas muscle thickness and area in patients with liver cirrhosis and sarcopenia

Моцюк¹,

Пентюк²

2021

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. Sarcopenia is a typical complication of liver cirrhosis (LC) and is associated with a poor prognosis. The skeletal muscle index is the most studied radiological marker of sarcopenia, but it’s using requires the qualification of a radiologist, specialized software, time reserve. The aim of the study: to investigate the relationship between different radiological markers of skeletal muscle mass, to determine their reference ranges for Ukrainian population and to assess their diagnostic and prognostic value in patients with LC. The study involved 216 healthy people and 147 patients with LC. During 18 months of follow-up 45 patients died from LC complications. Skeletal muscles were assessed by computed tomography. Skeletal muscle index (SMI), psoas muscle index (PMI), and transverse psoas muscle thickness (TPMT) at L3 were determined. Statistical data processing was performed in SPSS22. Diagnostic and prognostic value of SMI, PMI, TPMT were studied in ROC analysis. It was found that in Ukrainian population the reference ranges of SMI are >52.2 / 39.3 cm2/m2, PMI>6. 44 / 3.49 cm2/m2, TPMT>11.1 / 7.42 mm/m, in men / women, respectively. Sarcopenia was diagnosed in 54.9% and 86.3% of LC class B and C patients. PMI and TPMT had a high diagnostic value in sarcopenia detection (SMI≤52.2 and ≤39.3 cm2/m2) in male and female LC patients (AUC PMI 0.899 and 0.955, p˂0.001, AUC TPMT 0.884 and 0.942, p˂0.001). SMI, PMI and TPMT predicted one-and-a-half-year mortality in male and female LC patients (AUC SMI 0.815 and 0.786, p<0.001; AUC PMI 0.745 and 0.804, p<0.001; AUC TPMT 0.752 and 0.871, p<0.001). The optimal cut-off values for predicting death in male and female are: SMI≤49.1 and ≤38.4 cm2/m2; PMI≤5.99 and ≤3.30 cm2/m2; TPMT≤11.0 and ≤6.70 mm/m. Thus, routine assessment of PMI and TPMT in LC can identify patients with sarcopenia and high risk of complications.

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Cut-off values of skeletal muscle index and psoas muscle index at L3 vertebra level by computerized tomography to assess low muscle mass

Cited by 82 publications

References 27 publications

The Psoas Muscle Index and Retrospective Clinical Frailty Scale Score Predict Overall Survival in Patients With Multiple Myeloma

The Psoas Muscle Index and Retrospective Clinical Frailty Scale Score Predict Overall Survival in Patients With Multiple Myeloma

Orthogeriatrics: a vital requirement for improving fragility fracture patient care internationally with particular reference to Turkey

Diagnostic and prognostic value of psoas muscle thickness and area in patients with liver cirrhosis and sarcopenia

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