Cutaneous adverse effects of biologic drugs in psoriasis: a literature review

Baglama, Špela Šuler; Trčko, Katarina

doi:10.15570/actaapa.2021.35

Cited by 1 publication

(1 citation statement)

References 38 publications

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“…Psoriasis is a chronic immune-mediated inflammatory dermatoses of the skin, and usually consist of recurrent indolent red, scaly, sharply demarcated, indurated plaques or patches, which present particularly over the extensor surfaces of knee and elbow, trunk, and scalp. Plaque psoriasis (PP) is the most common type of psoriasis, accounting for approximately 85% of all cases, and it affects about 2.5% of the population in Western countries [ 1 , 2 , 3 , 4 , 5 ].…”

Section: Background and Objectivesmentioning

confidence: 99%

CT Patterns of Interstitial Lung Disease in Patients with Plaque Psoriasis: A Retrospective Case Series Study

Rizzetto,

Tagliati,

Fogante

et al. 2023

Medicina

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Background and Objectives: Recently published articles reported an association between psoriasis and interstitial lung diseases (ILDs). The aim of this study is to evaluate the differences in ILD computed tomography (CT) patterns between smoker and never smoker plaque psoriasis (PP) patients under topical treatment without psoriatic arthritis (PA), inflammatory bowel disease (IBD) or connective tissue diseases (CTDs). Matherials and Methods: Two radiologists evaluated chest CT examinations of 65 patients (33 smokers, 32 never smokers) with PP. Results: Usual interstitial pneumonia (UIP) pattern was diagnosed in 36 patients, nonspecific interstitial pneumonia pattern in 19, hypersensitivity pneumonitis in 7 and pleuropulmonary fibroelastosis (PPFE) in 3 patients. UIP pattern showed a statistically significant higher frequency in smoker patients (p = 0.0351). Respiratory symptoms were reported in 80% of patients. Conclusions: ILDs seems to represent a new comorbidity associated with psoriasis. Moreover, a statistically significant association between smokers and UIP pattern in PP patients is found. Respiratory symptoms should be evaluated in PP patients, in collaboration with a radiologist and a pneumologist. However, further studies are required to better understand the epidemiology of ILDs in PP patients.

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